About 80% of brain disorders have a genetic basis. The pathogenesis of most
neurodegenerative diseases is associated with a myriad of genetic defects, epigenetic …

Autoimmune hemolytic anemia (AIHA) is due to autoantibodies with or without complement
activation and involves cellular and cytokine dysregulation. Here, we investigated cytokine …

Background A distinct phenotype in Coronavirus disease 2019 (Covid-19) was observed in
severe patients, consisting of a highly impaired interferon (IFN) type I response, an …

Background: TNF-α has a dual role in multiple sclerosis (MS), contributing to both protective
and harmful effects. It activates immune cells, promotes the formation of inflammatory lesions …

The pathogenic roles of Interleukine-16 (IL-16), CCL27, tumor necrosis factor-related
apoptosis-inducing ligand (TRAIL), and B-cell activating factor (BAFF) has been shown in …

Background: Multiple sclerosis (MS), a chronic inflammatory disorder, affects the central
nervous system via myelin degradation. The cause of MS is not fully known, but during …

Tumor necrosis factor-alpha TNF-α) is a pro-inflammatory cytokine that is involved in the
pathogenesis of Multiple Sclerosis. The current study was designed to examine the …

Background Epidemiological studies about the association between genetic polymorphisms
in TNFA, TNFB, and IFNG and the risk for multiple sclerosis (MS) have been performed …

Background Our previous study has reported that interleukin-16 (IL-16) genetic
polymorphisms are significantly related to chronic hepatitis B (CHB) and hepatitis B virus …

Objective: Interleukin 17 (IL-17) plays an important role in the inflammation of the gastric
mucosa and, in severe cases, the development of gastric cancer. Thus, the authors aimed to …