[Retracted] Apoptosis and Molecular Targeting Therapy in Cancer

M Hassan, H Watari, A AbuAlmaaty… - BioMed research …, 2014 - Wiley Online Library
Apoptosis is the programmed cell death which maintains the healthy survival/death balance
in metazoan cells. Defect in apoptosis can cause cancer or autoimmunity, while enhanced …

Apoptotic cell signaling in cancer progression and therapy

J Plati, O Bucur, R Khosravi-Far - Integrative biology, 2011 - academic.oup.com
Apoptosis is a tightly regulated cell suicide program that plays an essential role in the
development and maintenance of tissue homeostasis by eliminating unnecessary or harmful …

Effects of fungal based bioactive compounds on human health

N Rousta, M Aslan, M Yesilcimen Akbas… - Critical reviews in …, 2024 - Taylor & Francis
Since the first years of history, microbial fermentation products such as bread, wine, yogurt
and vinegar have always been noteworthy regarding their nutritional and health effects …

[HTML][HTML] Roles of c-FLIP in apoptosis, necroptosis, and autophagy

AR Safa - Journal of carcinogenesis & mutagenesis, 2013 - ncbi.nlm.nih.gov
Abstract Cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein (c-FLIP) is a
major antiapoptotic protein and an important cytokine and chemotherapy resistance factor …

Targeting the anti-apoptotic protein c-FLIP for cancer therapy

AR Safa, KE Pollok - Cancers, 2011 - mdpi.com
Cellular FLICE (FADD-like IL-1beta-converting enzyme)-inhibitory protein (c-FLIP) is a major
resistance factor and critical anti-apoptotic regulator that inhibits tumor necrosis factor-alpha …

Targeting c-FLIP in cancer

S Shirley, O Micheau - Cancer letters, 2013 - Elsevier
Cellular-FLICE inhibitory protein (c-FLIP) is a key anti-apoptotic regulator that inhibits cell
death mediated by the death receptors Fas, DR4, DR5, and TNF-R1. Three splice variants of …

Withaferin A: a dietary supplement with promising potential as an anti-tumor therapeutic for cancer treatment-pharmacology and mechanisms

Z Xing, A Su, L Mi, Y Zhang, T He, Y Qiu… - Drug Design …, 2023 - Taylor & Francis
Cancer, as the leading cause of death worldwide, poses a serious threat to human health,
making the development of effective tumor treatments a significant challenge. Natural …

Chemerin and cancer

O Treeck, C Buechler, O Ortmann - International journal of molecular …, 2019 - mdpi.com
Chemerin is a multifunctional adipokine with established roles in inflammation,
adipogenesis and glucose homeostasis. Increasing evidence suggest an important function …

Immediate early response genes and cell transformation

S Healy, P Khan, JR Davie - Pharmacology & therapeutics, 2013 - Elsevier
Cancer has been described as not one disease, but several, each with unique
characteristics, symptoms, prognostics and outcomes. Underlying this complexity is a …

FLIP as a therapeutic target in cancer

L Humphreys, M Espona‐Fiedler… - The FEBS …, 2018 - Wiley Online Library
One of the classic hallmarks of cancer is disruption of cell death signalling. Inhibition of cell
death promotes tumour growth and metastasis, causes resistance to chemo‐and …