Unveiling the macrophage dynamics in osteoarthritic joints: From inflammation to therapeutic strategies
N Gaigeard, A Cardon, B Le Goff, J Guicheux… - Drug Discovery …, 2024 - Elsevier
Highlights•Synovitis plays a central role in osteoarthritis (OA) pathophysiology.•Various
subsets of macrophages are present and play distinct roles in the synovium.•Synovial …
subsets of macrophages are present and play distinct roles in the synovium.•Synovial …
Single-cell technology for drug discovery and development
A Zhang, J Zou, Y Xi, L Gao, F Deng, Y Liu… - Frontiers in Drug …, 2024 - frontiersin.org
The success rate of drug development today remains low, with long development cycles and
high costs, especially in areas such as oncology, neurology, immunology, and infectious …
high costs, especially in areas such as oncology, neurology, immunology, and infectious …