An overview on the synthetic urease inhibitors with structure-activity relationship and molecular docking
W Yang, Q Feng, Z Peng, G Wang - European Journal of Medicinal …, 2022 - Elsevier
Urease is a kind of enzyme which could be found in various bacteria, fungi, plants, and
algae, which can quickly catalyze the hydrolysis of urea into ammonia and carbon dioxide …
algae, which can quickly catalyze the hydrolysis of urea into ammonia and carbon dioxide …
Synthesis, molecular docking, acetylcholinesterase and butyrylcholinesterase inhibitory potential of thiazole analogs as new inhibitors for Alzheimer disease
A series of thirty (30) thiazole analogs were prepared, characterized by 1 H NMR, 13 C NMR
and EI-MS and evaluated for Acetylcholinesterase and butyrylcholinesterase inhibitory …
and EI-MS and evaluated for Acetylcholinesterase and butyrylcholinesterase inhibitory …
Synthesis, α-glucosidase inhibition and molecular docking study of coumarin based derivatives
We have synthesized seventeen Coumarin based derivatives (1–17), characterized by 1
HNMR, 13 CNMR and EI-MS and evaluated for α-glucosidase inhibitory potential. Among …
HNMR, 13 CNMR and EI-MS and evaluated for α-glucosidase inhibitory potential. Among …
Synthesis and evaluation of 1, 3, 5-triaryl-2-pyrazoline derivatives as potent dual inhibitors of urease and α-glucosidase together with their cytotoxic, molecular …
In the present work, a concise library of 1, 3, 5-triaryl-2-pyrazolines (2a–2q) was designed
and synthesized by employing a multistep strategy, and the newly synthesized compounds …
and synthesized by employing a multistep strategy, and the newly synthesized compounds …
Synthesis of novel Schiff bases using green chemistry techniques; antimicrobial, antioxidant, antiurease activity screening and molecular docking studies
Schiff base derivatives were synthesized in this study via conventional, microwave
irradiation and ultrasound sonication methods. Optimization conditions were examined for …
irradiation and ultrasound sonication methods. Optimization conditions were examined for …
[HTML][HTML] In silico molecular docking: Evaluation of coumarin based derivatives against SARS-CoV-2
Background The unique anthropological coronavirus which has been titled as SARS-CoV-2
was originally arisen in late 2019 in Wuhan, China affecting respiratory infection named as …
was originally arisen in late 2019 in Wuhan, China affecting respiratory infection named as …
Synthesis and in vitro acetylcholinesterase and butyrylcholinesterase inhibitory potential of hydrazide based Schiff bases
To discover multifunctional agents for the treatment of Alzheimer's disease, a series of
hydrazide based Schiff bases were designed and synthesized based on multitarget-directed …
hydrazide based Schiff bases were designed and synthesized based on multitarget-directed …
Synthesis of 4-thiazolidinone analogs as potent in vitro anti-urease agents
Thiazolidinone analogs 1–20 were synthesized, characterized by 1 H NMR and EI–MS and
investigated for urease inhibitory activity. All twenty (20) analogs exhibited varied degree of …
investigated for urease inhibitory activity. All twenty (20) analogs exhibited varied degree of …
A novel hybrid biocatalyst from immobilized Eversa® Transform 2.0 lipase and its application in biolubricant synthesis
I Germano de Sousa, A Valério Chaves… - Biocatalysis and …, 2024 - Taylor & Francis
In this study, a Taguchi experimental design was used for optimzing the immobilization of
the lipase Eversa® Transform 2.0 (EVS) onto a hybrid support consisting of chitosan (CHI) …
the lipase Eversa® Transform 2.0 (EVS) onto a hybrid support consisting of chitosan (CHI) …
Inhibition of Helicobacter pylori and Its Associated Urease by Palmatine: Investigation on the Potential Mechanism
JT Zhou, CL Li, LH Tan, YF Xu, YH Liu, ZZ Mo… - PLoS one, 2017 - journals.plos.org
In this paper, we evaluated the anti-Helicobacter pylori activity and the possible inhibitory
effect on its associated urease by Palmatine (Pal) from Coptis chinensis, and explored the …
effect on its associated urease by Palmatine (Pal) from Coptis chinensis, and explored the …