Despite efficient combination of the antiretroviral therapy (cART), which significantly
decreased mortality and morbidity of HIV-1 infection, a definitive HIV cure has not been …

In tandem with the ever‐increasing aging population in low and middle‐income countries,
the burden of dementia is rising on the African continent. Dementia prevalence varies from …

Human Immunodeficiency Virus (HIV) is widely acknowledged for its profound impact on the
immune system. Although HIV primarily affects peripheral CD4 T cells, its influence on the …

The prevalence of the most severe forms of HIV-associated neurocognitive disorders
(HAND) is decreasing due to worldwide availability and high efficacy of antiretroviral …

Objective: The relationship of cerebrospinal fluid (CSF) extracellular vesicles to
neurocognitive impairment (NCI) in HIV-infected individuals is unclear. Here, we …

The activities of HIV‐1 in the central nervous system (CNS) are responsible for a
dysregulated neuroinflammatory response and the subsequent development of HIV …

Brain-derived neurotrophic factor (BDNF) is a major neurotrophin whose loss or interruption
is well established to have numerous intersections with the pathogenesis of progressive …

Subtype B HIV-1 reservoirs have been intensively investigated, but reservoirs in other
subtypes and how they respond to antiretroviral therapy (ART) is substantially less …

Objectives To analyze the effect of a comprehensive program of cognitive stimulation with
digital inclusion, physical activity and social interaction, called" Oficina da Lembrança"(OL) …

Objective CD16+/CD163+ macrophages (MΦs) and microglia accumulate in the brains of
patients with human immunodeficiency virus (HIV) encephalitis (HIVE), a neuropathological …