A Consensus Statement on acromegaly therapeutic outcomes

S Melmed, MD Bronstein, P Chanson… - Nature Reviews …, 2018 - nature.com
Abstract The 11th Acromegaly Consensus Conference in April 2017 was convened to
update recommendations on therapeutic outcomes for patients with acromegaly. Consensus …

Advances in therapeutic peptides targeting G protein-coupled receptors

AP Davenport, CCG Scully, C de Graaf… - Nature Reviews Drug …, 2020 - nature.com
Dysregulation of peptide-activated pathways causes a range of diseases, fostering the
discovery and clinical development of peptide drugs. Many endogenous peptides activate G …

Acromegaly: an endocrine society clinical practice guideline

L Katznelson, ER Laws Jr, S Melmed… - The Journal of …, 2014 - academic.oup.com
Objective: The aim was to formulate clinical practice guidelines for acromegaly. Participants:
The Task Force included a chair selected by the Endocrine Society Clinical Guidelines …

International Union of Basic and Clinical Pharmacology. CV. Somatostatin receptors: structure, function, ligands, and new nomenclature

T Günther, G Tulipano, P Dournaud, C Bousquet… - Pharmacological …, 2018 - Elsevier
Somatostatin, also known as somatotropin-release inhibitory factor, is a cyclopeptide that
exerts potent inhibitory actions on hormone secretion and neuronal excitability. Its …

Expert consensus document: a consensus on the medical treatment of acromegaly

A Giustina, P Chanson, D Kleinberg… - Nature Reviews …, 2014 - nature.com
Abstract In March 2013, the Acromegaly Consensus Group met to revise and update
guidelines for the medical treatment of acromegaly. The meeting comprised experts skilled …

Somatostatin receptors: from signaling to clinical practice

M Theodoropoulou, GK Stalla - Frontiers in neuroendocrinology, 2013 - Elsevier
Somatostatin is a peptide with a potent and broad antisecretory action, which makes it an
invaluable drug target for the pharmacological management of pituitary adenomas and …

Acromegaly pathogenesis and treatment

S Melmed - The Journal of clinical investigation, 2009 - Am Soc Clin Investig
Dysregulated growth hormone (GH) hypersecretion is usually caused by a GH-secreting
pituitary adenoma and leads to acromegaly—a disorder of disproportionate skeletal, tissue …

Guidelines for acromegaly management: an update

S Melmed, A Colao, A Barkan, M Molitch… - Journal of Clinical …, 2009 - cdr.lib.unc.edu
" Objective: The Acromegaly Consensus Group reconvened in November 2007 to update
guidelines for acromegaly management. Participants: The meeting participants comprised …

American Association of Clinical Endocrinologists medical guidelines for clinical practice for the diagnosis and treatment of acromegaly-2011 update

L Katznelson, JLD Atkinson, DM Cook… - Endocrine …, 2011 - endocrinepractice.org
AACE= American Association of Clinical Endocrinologists; BEL=“best evidence” level;
BMD= bone mineral density; CPAP= continuous positive airway pressure; CPG= clinical …

Place of cabergoline in acromegaly: a meta-analysis

L Sandret, P Maison, P Chanson - The Journal of Clinical …, 2011 - academic.oup.com
Context: Cabergoline is widely considered to be poorly effective in acromegaly. Objective:
The aim of this study was to obtain a more accurate picture of the efficacy of cabergoline in …