Vaccines as treatments for prostate cancer

I Rastogi, A Muralidhar, DG McNeel - Nature Reviews Urology, 2023 - nature.com
Prostate cancer is a leading cause of death in men worldwide. For over 30 years, growing
interest has focused on the development of vaccines as treatments for prostate cancer, with …

Immunotherapy in treatment of metastatic prostate cancer: An approach to circumvent immunosuppressive tumor microenvironment

BL Sun - The Prostate, 2021 - Wiley Online Library
Prostate cancer is the second most common cause of cancer‐related death in men in the
United States and the fifth worldwide. Most prostate cancer arises as an androgen …

A phase Ib study of atezolizumab with radium-223 dichloride in men with metastatic castration-resistant prostate cancer

L Fong, MJ Morris, O Sartor, CS Higano, L Pagliaro… - Clinical Cancer …, 2021 - AACR
Purpose: Men with metastatic castration-resistant prostate cancer (mCRPC) have limited
treatment options after progressing on hormonal therapy and chemotherapy. Here, we …

The immunotherapy and immunosuppressive signaling in therapy-resistant prostate cancer

P Xu, LJ Wasielewski, JC Yang, D Cai, CP Evans… - Biomedicines, 2022 - mdpi.com
Prostate cancer is one of the most common malignant tumors in men. Initially, it is androgen-
dependent, but it eventually develops into castration-resistant prostate cancer (CRPC) …

[HTML][HTML] Prostate cancer bone metastases biology and clinical management

E Archer Goode, N Wang… - Oncology Letters, 2023 - spandidos-publications.com
Prostate cancer (PCa) is one of the most prominent causes of cancer‑related mortality in the
male population. A highly impactful prognostic factor for patients diagnosed with PCa is the …

Immunotherapy in prostate cancer: state of art and new therapeutic perspectives

FM Maselli, F Giuliani, C Laface, M Perrone… - Current …, 2023 - mdpi.com
Prostate cancer (PC) is the most common type of tumor in men. In the early stage of the
disease, it is sensitive to androgen deprivation therapy. In patients with metastatic castration …

[HTML][HTML] Vaccinating against cancer: getting to prime time

R Chang, JL Gulley, L Fong - Journal for immunotherapy of cancer, 2023 - ncbi.nlm.nih.gov
Immunotherapies, such as immune checkpoint inhibitors, cellular therapies, and T-cell
engagers, have fundamentally changed our approach to treating cancer. However …

Advances in and prospects of immunotherapy for prostate cancer

D Liu, L Wang, Y Guo - Cancer Letters, 2024 - Elsevier
Immunotherapy has shown promising therapeutic effects in hematological malignancies and
certain solid tumors and has emerged as a critical and highly potential treatment modality for …

Developments in combining targeted radionuclide therapies and immunotherapies for cancer treatment

CP Kerr, JJ Grudzinski, TP Nguyen, R Hernandez… - Pharmaceutics, 2022 - mdpi.com
Targeted radionuclide therapy (TRT) and immunotherapy are rapidly growing classes of
cancer treatments. Basic, translational, and clinical research are now investigating …

Molecular heterogeneity in prostate cancer and the role of targeted therapy

S Khan, P Baligar, C Tandon, J Nayyar, S Tandon - Life Sciences, 2024 - Elsevier
Data collected from large-scale studies has shown that the incidence of prostate cancer
globally is on the rise, which could be attributed to an overall increase in lifespan. So, the …