Changes in the intestinal microbiome have been associated with obesity and type 2
diabetes, in epidemiological studies and studies of the effects of fecal transfer in germ-free …

Cardiovascular disease (CVD) is a health problem worldwide, and elevated cholesterol
levels are a key risk factor for the disease. Dysbiotic gut microbiota has been shown to be …

Consumption of dietary lipids, such as cholesterol, modulates the gut microbiome with
consequences for host health through the production of microbiome-derived metabolites …

Hypercholesterolemia plays a causal role in the development of atherosclerosis and is one
of the main risk factors for cardiovascular disease (CVD), the leading cause of death …

Microbial trimethylamine (TMA)-lyase activity promotes the development of atherosclerosis
by generating of TMA, the precursor of TMA N-oxide (TMAO). TMAO is well documented, but …

Importance Metabolomics reflect the net effect of genetic and environmental influences and
thus provide a comprehensive approach to evaluating the pathogenesis of complex …

Abstract Trimethylamine-N-oxide (TMAO), a derivative from the gut microbiota metabolite
trimethylamine (TMA), has been identified to be an independent risk factor for promoting …

Embraced with apolipoproteins (Apo) B and Apo E, triglyceride-enriched very-low-density
lipoprotein (VLDL) is secreted by the liver into circulation, mainly during post-meal hours …

Cardiovascular diseases (CVD) are a group of disorders of the heart and blood vessels and
remain the leading cause of morbidity and mortality worldwide. Over the past decades …

The gut microbiota and liver cancer have a complex interaction. However, the role of gut
microbiome in liver tumor initiation remains unknown. Herein, liver cancer was induced …