Pathogenesis and treatment options of cancer related anemia: perspective for a targeted mechanism-based approach

C Madeddu, G Gramignano, G Astara… - Frontiers in …, 2018 - frontiersin.org
Cancer-related anemia (CRA) is a common sign occurring in more than 30% of cancer
patients at diagnosis before the initiation of antineoplastic therapy. CRA has a relevant …

Impact of hemoglobin levels and anemia on mortality in acute stroke: analysis of UK regional registry data, systematic review, and meta‐analysis

RS Barlas, K Honney, YK Loke, SJ McCall… - Journal of the …, 2016 - Am Heart Assoc
Background The impact of hemoglobin levels and anemia on stroke mortality remains
controversial. We aimed to systematically assess this association and quantify the evidence …

Perioperative care of patients at high risk for stroke during or after non-cardiac, non-neurologic surgery: consensus statement from the Society for Neuroscience in …

GA Mashour, LE Moore, AV Lele… - Journal of …, 2014 - journals.lww.com
Perioperative stroke can be a catastrophic outcome for surgical patients and is associated
with increased morbidity and mortality. This consensus statement from the Society for …

Vascular risk factors and cognitive impairment in chronic kidney disease: the Chronic Renal Insufficiency Cohort (CRIC) study

MK Tamura, D Xie, K Yaffe, DL Cohen… - Clinical journal of the …, 2011 - journals.lww.com
Results Among 3591 participants, the mean age was 58.2±11.0 years, and the mean
estimated GFR (eGFR) was 43.4±13.5 ml/min per 1.73 m 2. Cognitive impairment was …

Anemia management after acute brain injury

C Lelubre, P Bouzat, IA Crippa, FS Taccone - Critical care, 2016 - Springer
Anemia is frequent among brain-injured patients, where it has been associated with an
increased risk of poor outcome. The pathophysiology of anemia in this patient population …

A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-κB promotes gastric tumour growth and angiogenesis

SY Nam, YS Ko, J Jung, J Yoon, YH Kim… - British journal of …, 2011 - nature.com
Background: The underlying mechanisms involved in the activation of hypoxia-inducible
factor-1 (HIF-1) in gastric cancer remain unclear. As nuclear factor-κB (NF-κB) as well as HIF …

Anemia and red blood cell transfusion in neurocritical care

AH Kramer, DA Zygun - Critical care, 2009 - Springer
Introduction Anemia is one of the most common medical complications to be encountered in
critically ill patients. Based on the results of clinical trials, transfusion practices across the …

Selective β1-antagonism with bisoprolol is associated with fewer postoperative strokes than atenolol or metoprolol: a single-center cohort study of 44,092 consecutive …

C Ashes, S Judelman, DN Wijeysundera… - Survey of …, 2015 - journals.lww.com
In previous trials, metoprolol succinate, a nonselective β-blocker, reduced the risk of
perioperative myocardial infarction, but it doubled the incidence of postoperative stroke and …

Cerebral infarction in β-thalassemia intermedia: breaking the silence

KM Musallam, AT Taher, M Karimi, EA Rachmilewitz - Thrombosis research, 2012 - Elsevier
Despite remarkable advances in understanding cerebrovascular disease attributed to sickle
cell anemia, data from other hemoglobinopathies have only recently started to emerge …

[HTML][HTML] Asymptomatic brain magnetic resonance imaging abnormalities in splenectomized adults with thalassemia intermedia

AT Taher, KM Musallam, W Nasreddine… - Journal of Thrombosis …, 2010 - Elsevier
Background: A high incidence of thrombotic events in thalassemia intermedia (TI) patients
led to the identification of a hypercoagulable state. Brain involvement has not been widely …