Buprenorphine possesses many unique attributes that make it a practical agent for adults
and adolescents with opioid use disorder (OUD) and/or acute or chronic pain. Sublingual …

Low dose buprenorphine initiation, is an alternative method of initiating buprenorphine in
which the starting dose is very low and gradually increased to therapeutic levels over a …

Buprenorphine induction for treating opioid use disorder is being implemented in
emergency care. During this era of high-potency synthetic opioid use, novel and divergent …

Objectives: Patients with opioid use disorder (OUD) can initiate buprenorphine without
requiring a withdrawal period through a low-dose (sometimes referred to as “micro …

Background/objectives Micro-induction is a novel buprenorphine induction approach that
seeks to avoid withdrawal and minimize precipitated withdrawal, both barriers to standard …

Although expanding the availability of buprenorphine—a first-line pharmacotherapy for
opioid-use disorder (OUD)—has increased the capacity of healthcare systems to offer …

With the worst opioid overdose death crisis in the United States history, urgent new
approaches to assist people who use drugs onto medication for opioid use disorder are …

Abstract Introduction and Aims North America is currently experiencing an epidemic of
opioid overdose deaths, driven by the proliferation of fentanyl in the street drug market …

Substance use in pregnancy is common; nearly one of five of pregnant individuals have
pastmonth nicotine, alcohol, or illicit substance use, and more than one in 10 meet criteria …

Importance The rise of high-potency opioids such as fentanyl makes buprenorphine
initiation challenging due to the risks of precipitated withdrawal, prompting the exploration of …