Oral drug delivery platforms for biomedical applications

J Ouyang, Z Zhang, B Deng, J Liu, L Wang, H Liu… - Materials Today, 2023 - Elsevier
Oral administration is perhaps the most commonly used and acceptable route for drug
delivery to patients, mainly due to its non-invasiveness, simplicity, and versatility …

[HTML][HTML] Lipids in atherosclerosis: pathophysiology and the role of calculated lipid indices in assessing cardiovascular risk in patients with hyperlipidemia

M Gaggini, F Gorini, C Vassalle - International journal of molecular …, 2022 - mdpi.com
The role of lipids is essential in any phase of the atherosclerotic process, which is
considered a chronic lipid-related and inflammatory condition. The traditional lipid profile …

[HTML][HTML] Antiplatelet therapy after percutaneous coronary intervention

DJ Angiolillo, M Galli, JP Collet, A Kastrati… - …, 2022 - ncbi.nlm.nih.gov
Antiplatelet therapy is key to reducing local thrombotic complications and systemic
ischaemic events among patients undergoing percutaneous coronary interventions (PCI) …

Magnetic soft microfiberbots for robotic embolization

X Liu, L Wang, Y Xiang, F Liao, N Li, J Li, J Wang… - Science Robotics, 2024 - science.org
Cerebral aneurysms and brain tumors are leading life-threatening diseases worldwide. By
deliberately occluding the target lesion to reduce the blood supply, embolization has been …

Red blood cell distribution width: a simple parameter with multiple clinical applications

GL Salvagno, F Sanchis-Gomar… - Critical reviews in …, 2015 - Taylor & Francis
The red blood cell distribution width (RDW) is a simple and inexpensive parameter, which
reflects the degree of heterogeneity of erythrocyte volume (conventionally known as …

Neutrophil extracellular traps in atherosclerosis and atherothrombosis

Y Döring, O Soehnlein, C Weber - Circulation research, 2017 - Am Heart Assoc
Neutrophil extracellular traps expelled from suicidal neutrophils comprise a complex
structure of nuclear chromatin and proteins of nuclear, granular, and cytosolic origin. These …

[HTML][HTML] ROS in platelet biology: functional aspects and methodological insights

E Masselli, G Pozzi, M Vaccarezza… - International journal of …, 2020 - mdpi.com
Reactive oxygen species (ROS) and mitochondria play a pivotal role in regulating platelet
functions. Platelet activation determines a drastic change in redox balance and in platelet …

[HTML][HTML] Alternative pathways of IL-1 activation, and its role in health and disease

K Pyrillou, LC Burzynski, MCH Clarke - Frontiers in immunology, 2020 - frontiersin.org
Cytokines activate or inhibit immune cell behavior and are thus integral to all immune
responses. IL-1α and IL-1β are powerful apical cytokines that instigate multiple downstream …

Engineered nanoplatelets for targeted delivery of plasminogen activators to reverse thrombus in multiple mouse thrombosis models

J Xu, Y Zhang, J Xu, G Liu, C Di, X Zhao, X Li… - Advanced …, 2020 - Wiley Online Library
Rapid cut‐off of blood supply in diseases involving thrombosis is a major cause of morbidity
and mortality worldwide. However, the current thrombolysis strategies offer limited results …

Coronavirus disease 2019–associated coagulopathy

G Lippi, F Sanchis-Gomar, EJ Favaloro, CJ Lavie… - Mayo Clinic …, 2021 - Elsevier
Patients with the severe form of coronavirus disease 2019 (COVID-19) have been frequently
found to suffer from both arterial and venous thrombotic events due to the perpetuation of a …