Sea cucumber (Cucumaria frondosa) is the most abundant and widely distributed species in
the cold waters of North Atlantic Ocean. C. frondosa contains a wide range of bioactive …

The transient receptor potential (TRP) cation channel superfamily comprises more than 50
channels that play crucial roles in physiological processes. TRP channels are responsive to …

Inflammatory bowel disease, comprising Crohn's disease (CD) and ulcerative colitis (UC), is
often debilitating. The disease etiology is multifactorial, involving genetic susceptibility …

The demand and high market price for sea cucumber has led to the collapse of wild stocks
for many traditional species in Asia and the Indo-Pacific. New species have therefore been …

Chronic inflammation can extensively burden a healthcare system. Several synthetic anti-
inflammatory drugs are currently available in clinical practice, but each has its own side …

Inflammation is a defense mechanism of the body in response to harmful stimuli such as
pathogens, damaged cells, toxic compounds or radiation. However, chronic inflammation …

Ulcerative colitis (UC) is a chronic inflammatory bowel disease for which there is currently no
efficacious therapeutic drug with fewer side effects. Therefore, the development of …

Inflammatory bowel disease (IBD) increases the risk of colorectal cancer, and it has the
potential to diminish the quality of life. Recent clinical and experimental evidence …

Inflammatory bowel diseases (IBD) are chronic inflammatory disorders with increasing
incidence and prevalence worldwide. Here, we investigated thymoquinone (TQ), a naturally …

The occurrence of intestinal diseases such as colon cancer is closely related to the intestinal
flora. Lactobacillus fermentum is a gut probiotic that plays an important role in chronic …