Most people associate fluoride with the practice of intentionally adding fluoride to public
drinking water supplies for the prevention of tooth decay. However, fluoride can also enter …

Increasing human activities have modified the global cycle of heavy metals, non metals and
metalloids. Both arsenic and fluoride are ubiquitous in the environment. Thousands of …

Fluoride is an effective caries prophylactic, but at high doses can also be an environmental
health hazard. Acute or chronic exposure to high fluoride doses can result in dental enamel …

There has been much discussion in recent years regarding the most appropriate follow-up
testing in vivo when positive results are obtained in vitro but the in vivo micronucleus (MN) …

A working group convened at the 2009 5th IWGT to discuss possibilities for improving in vivo
genotoxicity assessment by investigating possible links to standard toxicity testing. The …

Objectives: The aim of the present study was to comparatively evaluate the DNA damage
(micronucleus) and cellular death (pyknosis, karyolysis and karyorrhexis) of exfoliated …

Arsenic and fluoride are major contaminants of drinkingwater. Mechanisms of toxicity
following individual exposure to arsenic or fluoride are well known. However, it is not explicit …

Background Despite wide use as a diagnostic tool in medical and dental practice,
radiography can induce cytotoxic effects and genetic damage. Objective To evaluate DNA …

summary Mineral trioxide aggregate (MTA) and Portland cement are being used in dentistry
as root‐end‐filling material for periapical surgery and for the sealing of communications …

Genotoxicity is the ability of an agent to produce damage on the DNA molecule. Considering
the strong evidence for a relationship between genetic damage and carcinogenesis, to …