Continuous proliferation of tumor cells requires constant adaptations of energy metabolism
to rapidly fuel cell growth and division. This energetic adaptation often comprises …

Mitochondria are dynamic organelles managing crucial processes of cellular metabolism
and bioenergetics. Enabling rapid cellular adaptation to altered endogenous and …

Abstract Background HIF1A (Hypoxia-Inducible-Factor 1A) expression in solid tumors is
relevant to establish resistance to therapeutic approaches. The use of compounds direct …

It remains unknown whether and how intestinal stem cells (ISCs) adapt to inflammatory
exposure and whether the adaptation leaves scars that will affect their subsequent …

Succinate dehydrogenase inhibitors (SDHi) are fungicides used to control the proliferation of
pathogenic fungi in crops. Their mode of action is based on blocking the activity of succinate …

Additive manufacturing continues to evolve as a powerful tool for the fabrication of tissue‐
engineered scaffolds and medical devices. With this evolution, a library of materials with a …

Succinate receptor GPR91 is one of G protein‐coupled receptors (GPCRs), and is
expressed in a variety of cell types and tissues. Succinate is its natural ligand, and its …

Reprogramming of cellular metabolism is now considered one of the hallmarks of cancer.
Most malignant cells present with altered energy metabolism which is associated with …

The aim was to assess the suitability of three nano-based transdermal drug delivery systems
containing ibuprofen: a nano-emulsion, a nano-emulgel, and a colloidal suspension with …

Succinate dehydrogenase (SDH), also named as complex II or succinate: quinone
oxidoreductases (SQR) is a critical enzyme in bioenergetics and metabolism. This is …