Modifiable risk and protective factors for boosting brain and cognitive development and
preventing neurodegeneration and cognitive decline are embraced in neuroimaging …

Modern brainwide transcriptional atlases provide unprecedented opportunities for
investigating the molecular correlates of brain organization, as quantified using noninvasive …

A hallmark of nervous system aging is a decline of white matter volume and function, but the
underlying mechanisms leading to white matter pathology are unknown. In the present …

Our understanding of the genetics of the human cerebral cortex is limited both in terms of the
diversity and the anatomical granularity of brain structural phenotypes. Here we conducted a …

Higher educational attainment is observationally associated with lower risk of Alzheimer's
disease. However, the biological mechanisms underpinning this association remain unclear …

Preadolescence is a critical period characterized by dramatic morphological changes and
accelerated cortico-subcortical development. Moreover, the coordinated development of …

Cortical morphology is a key determinant of cognitive ability and mental health. Its
development is a highly intricate process spanning decades, involving the coordinated …

The cerebral ventricles are recognized as windows into brain development and disease, yet
their genetic architectures, underlying neural mechanisms and utility in maintaining brain …

It is well documented that some brain regions, such as association cortices, caudate, and
hippocampus, are particularly prone to age-related atrophy, but it has been hypothesized …

Introduction Treatment of severe mental illness (SMI) symptoms, especially negative
symptoms and cognitive dysfunction in schizophrenia, remains a major unmet need. There …