Human leukocyte antigen (HLA) and immune regulation: how do classical and non-classical HLA alleles modulate immune response to human immunodeficiency …

NB Crux, S Elahi - Frontiers in immunology, 2017 - frontiersin.org
The genetic factors associated with susceptibility or resistance to viral infections are likely to
involve a sophisticated array of immune response. These genetic elements may modulate …

Maternal KIR and fetal HLA-C: a fine balance

O Chazara, S Xiong, A Moffett - Journal of leukocyte biology, 2011 - academic.oup.com
ABSTRACT NK cell effector function is regulated by a range of activating and inhibitory
receptors, and many of their known ligands are MHC class I molecules. Human NK …

Common and well‐documented HLA alleles: 2012 update to the CWD catalogue

SJ Mack, P Cano, JA Hollenbach, J He… - Tissue …, 2013 - Wiley Online Library
We have updated the catalogue of common and well‐documented (CWD) human leukocyte
antigen (HLA) alleles to reflect current understanding of the prevalence of specific allele …

Common and well-documented HLA alleles: report of the Ad-Hoc committee of the american society for histocompatiblity and immunogenetics

P Cano, W Klitz, SJ Mack, M Maiers, SGE Marsh… - Human immunology, 2007 - Elsevier
In histocompatibility testing some genotype ambiguities are almost always resolved into the
genotype with the most common alleles. To achieve unambiguous assignments additional …

HLA DNA sequence variation among human populations: molecular signatures of demographic and selective events

S Buhler, A Sanchez-Mazas - PloS one, 2011 - journals.plos.org
Molecular differences between HLA alleles vary up to 57 nucleotides within the peptide
binding coding region of human Major Histocompatibility Complex (MHC) genes, but it is still …

HLA class I homozygosity accelerates disease progression in human immunodeficiency virus type 1 infection

J Tang, C Costello, IPM Keet, C Rivers… - AIDS research and …, 1999 - liebertpub.com
Polymorphic products of HLA class I genes restrict cytotoxic T lymphocyte responses to the
constantly evolving spectrum of HIV-1 antigens. Accordingly, homozygosity at class I loci can …

Nomenclature for factors of the HLA system, 1998

JG Bodmer, SGE Marsh, ED Albert, WF Bodmer… - Vox sanguinis, 1999 - karger.com
In addition the change of name of the gene HLA-DNA to HLA-DOA, as published in the
monthly updates, was confirmed, following further results showing that the gene codes for …

CD8 T-cell recognition of multiple epitopes within specific Gag regions is associated with maintenance of a low steady-state viremia in human immunodeficiency virus …

C Geldmacher, JR Currier, E Herrmann… - Journal of …, 2007 - Am Soc Microbiol
The importance of HLA class I-restricted CD8 T-cell responses in the control of human
immunodeficiency virus (HIV) infection is generally accepted. While several studies have …

HLA‐C as a mediator of natural killer and T‐cell activation: spectator or key player?

ME Blais, T Dong, S Rowland‐Jones - Immunology, 2011 - Wiley Online Library
The biochemical properties of the HLA‐C antigen differ substantially from those of HLA‐A
and‐B molecules. For this reason, HLA‐C diversity and expression at the cell surface are …

Favorable and unfavorable HLA class I alleles and haplotypes in Zambians predominantly infected with clade C human immunodeficiency virus type 1

J Tang, S Tang, E Lobashevsky, AD Myracle… - Journal of …, 2002 - Am Soc Microbiol
The setpoint of viral RNA concentration (viral load [VL]) during chronic human
immunodeficiency virus type 1 (HIV-1) infection reflects a virus-host equilibration closely …