Mechanical properties of extracellular matrices (ECMs) regulate essential cell behaviours,
including differentiation, migration and proliferation, through mechanotransduction. Studies …

Tissue repair after trauma and infection has always been a difficult problem in regenerative
medicine. Hydrogels have become one of the most important scaffolds for tissue …

The aberrant mechanical microenvironment in degenerated tissues induces misdirection of
cell fate, making it challenging to achieve efficient endogenous regeneration. Herein, a …

The skeletal muscle microenvironment transiently remodels and stiffens after exercise and
injury, as muscle ages, and in myopathic muscle; however, how these changes in stiffness …

Mechanobiology has underpinned many scientific advances in understanding how
biophysical and biomechanical cues regulate cell behavior by identifying mechanosensitive …

Decellularized materials (DMs) are attracting more and more attention because of their
native structures, comparatively high bioactivity, low immunogenicity and good …

Stem cell therapies have made great progress in the treatment of diabetic wounds during
recent decades, while their short in vivo residence, alloimmune reactions, undesired …

The cross-talk between stem cells and their microenvironment has been shown to have a
direct impact on stem cells' decisions about proliferation, growth, migration, and …

Chronic wounds, such as diabetic foot ulcers (DFU), are a serious clinical problem. It is a
challenge for the conventional wound dressings to achieve the desirable therapeutic …

The clinical translation of mesenchymal stromal cell (MSC)‐based therapies remains
challenging due to rapid cell death and poor control over cell behavior. Compared to …