Alarmins are endogenous, constitutively expressed, chemotacting and immune activating
proteins or peptides released because of non-programmed cell death (ie infections, trauma …

S100A12 is a member of the S100 family of EF-hand calcium-binding proteins. Human
S100A12 is predominantly expressed and secreted by neutrophil granulocytes and …

S100A12 is a member of the S100 family of calcium‐binding proteins with important
extracellular activities. In recent years, investigators across a number of fields have …

Background Alterations in the advanced glycation end-products (AGE)—receptor of AGE
(RAGE) system are linked to several chronic diseases, which may result from vascular …

Disruption of the barrier function of skin increases transepidermal water loss and up-
regulates inflammatory pathways in the epidermis. Consequently, sustained expression of …

Expression of S100A12, a small calcium-binding protein, by neutrophils and monocytes/
macrophages induces proinflammatory responses via ligation with the receptor for …

Objective Patients with type 2 diabetes mellitus (T2DM) are at high risk for development of
atherosclerosis and cardiovascular events. Serum S100A12 levels have been reported to be …

Objective Previous gene expression analyses seeking genes specific to antineutrophil
cytoplasmic antibody-associated vasculitis (AAV) have been limited due to crude cell …

Severe acute pancreatitis is a life threatening disease with a high rate of mortality, but its
treatments are still controversial. The purpose of this study is to investigate the potential …

Background: The calcium-binding protein S100A12 (EN-RAGE) causes inflammation
through interaction with the multiligand receptor for advanced glycation end products …