Mesenchymal stem cells (MSCs) are multipotent adult cells with self-renewing capacities.
MSCs display specific properties, such as the ability to repair damaged tissues, resulting in …

Epilepsy is a chronic non-infectious disease of the brain, characterized primarily by recurrent
unprovoked seizures, defined as an episode of disturbance of motor, sensory, autonomic, or …

Stem cells are a versatile source for cell therapy. Their use is particularly significant for the
treatment of neurological disorders for which no definitive conventional medical treatment is …

Background and aims Refractory epilepsy is also known as drug-resistant epilepsy with
limited clinical treatment. Benefitting from its safety and easy availability, olfactory mucosa …

Objectives It has been proven that extracellular HMGB1 is involved in progression of
neurologic disorders, such as stroke, traumatic brain injury, meningitis and epilepsy …

Purpose Existing anti-epileptic drugs (AED) have limited efficiency in many patients,
necessitating the search for alternative approaches such as stem cell therapy. We report the …

Epilepsy is a life-threatening neurological disease that affects approximately 70 million
people worldwide. Although the vast majority of patients may be successfully managed with …

Many animal prototypes illustrating the various attributes of human temporal lobe epilepsy
(TLE) are available. These models have been invaluable for comprehending multiple …

There is a need among patients suffering from drug-resistant epilepsy (DRE) for more
efficient and less toxic treatments. The objective of the present study was to assess the …

Mononuclear cells (MNCs) and mesenchymal stem cells (MSCs) derived from the bone
marrow and other sources have received significant attention as donor cells for treating …