Cardiovascular magnetic resonance in acute st-segment–elevation myocardial infarction: Recent advances, controversies, and future directions

H Bulluck, R Dharmakumar, AE Arai, C Berry… - Circulation, 2018 - Am Heart Assoc
Although mortality after ST-segment elevation myocardial infarction (MI) is on the decline,
the number of patients developing heart failure as a result of MI is on the rise. Apart from …

[HTML][HTML] Cardiac Fibrosis in heart failure: Focus on non-invasive diagnosis and emerging therapeutic strategies

S Ravassa, B López, TA Treibel, G San José… - Molecular Aspects of …, 2023 - Elsevier
Heart failure is a leading cause of mortality and hospitalization worldwide. Cardiac fibrosis,
resulting from the excessive deposition of collagen fibers, is a common feature across the …

T1 mapping in cardiac MRI

D Radenkovic, S Weingärtner, L Ricketts, JC Moon… - Heart failure …, 2017 - Springer
Quantitative myocardial and blood T 1 have recently achieved clinical utility in numerous
pathologies, as they provide non-invasive tissue characterization with the potential to …

Myocardial infarct size by CMR in clinical cardioprotection studies: insights from randomized controlled trials

H Bulluck, M Hammond-Haley, S Weinmann… - JACC: Cardiovascular …, 2017 - jacc.org
Objectives: The aim of this study was to review randomized controlled trials (RCTs) using
cardiac magnetic resonance (CMR) to assess myocardial infarct (MI) size in reperfused …

[HTML][HTML] Defining left ventricular remodeling following acute ST-segment elevation myocardial infarction using cardiovascular magnetic resonance

H Bulluck, YY Go, G Crimi, AJ Ludman… - Journal of …, 2016 - Elsevier
Background The assessment of post-myocardial infarction (MI) left ventricular (LV)
remodeling by cardiovascular magnetic resonance (CMR) currently uses criteria defined by …

Left ventricular functional recovery of infarcted and remote myocardium after ST-segment elevation myocardial infarction (METOCARD-CNIC randomized clinical trial …

T Podlesnikar, G Pizarro, R Fernández-Jiménez… - Journal of …, 2020 - Springer
Background We aimed to evaluate the effect of early intravenous metoprolol treatment,
microvascular obstruction (MVO), intramyocardial hemorrhage (IMH) and adverse left …

Acute response in the noninfarcted myocardium predicts long-term major adverse cardiac events after STEMI

M Shanmuganathan, A Masi, MK Burrage… - Cardiovascular …, 2023 - jacc.org
Background Acute ST-segment elevation myocardial infarction (STEMI) has effects on the
myocardium beyond the immediate infarcted territory. However, pathophysiologic changes …

Changes in remote myocardial tissue after acute myocardial infarction and its relation to cardiac remodeling: a CMR T1 mapping study

PS Biesbroek, RP Amier, PFA Teunissen… - PLoS …, 2017 - journals.plos.org
Objectives To characterize the temporal alterations in native T1 and extracellular volume
(ECV) of remote myocardium after acute myocardial infarction (AMI), and to explore their …

Left ventricular adverse remodeling in ischemic heart disease: emerging cardiac magnetic resonance imaging biomarkers

C Calvieri, A Riva, F Sturla, L Dominici, L Conia… - Journal of Clinical …, 2023 - mdpi.com
Post-ischemic left ventricular (LV) remodeling is a biologically complex process involving
myocardial structure, LV shape, and function, beginning early after myocardial infarction (MI) …

Network model‐based screen for FDA‐approved drugs affecting cardiac fibrosis

AC Zeigler, AS Chandrabhatla… - CPT …, 2021 - Wiley Online Library
Cardiac fibrosis is a significant component of pathological heart remodeling, yet it is not
directly targeted by existing drugs. Systems pharmacology approaches have the potential to …