Galectin expression in cancer diagnosis and prognosis: A systematic review

VL Thijssen, R Heusschen, J Caers… - Biochimica et Biophysica …, 2015 - Elsevier
Galectins are a family of proteins that bind to specific glycans thereby deciphering the
information captured within the glycome. In the last two decades, several galectin family …

Sweetening the hallmarks of cancer: Galectins as multifunctional mediators of tumor progression

MR Girotti, M Salatino, T Dalotto-Moreno… - Journal of Experimental …, 2019 - rupress.org
Hanahan and Weinberg have proposed 10 organizing principles that enable growth and
metastatic dissemination of cancer cells. These distinctive and complementary capabilities …

Pectin–an emerging new bioactive food polysaccharide

EG Maxwell, NJ Belshaw, KW Waldron… - Trends in Food Science & …, 2012 - Elsevier
Pectin is a constituent of the cell walls of fruits and vegetables, and provides an important
source of dietary fibre, as well as being a functional ingredient in processed foods. In …

Biomarkers in cancer detection, diagnosis, and prognosis

S Das, MK Dey, R Devireddy, MR Gartia - Sensors, 2023 - mdpi.com
Biomarkers are vital in healthcare as they provide valuable insights into disease diagnosis,
prognosis, treatment response, and personalized medicine. They serve as objective …

Galectin targeted therapy in oncology: Current knowledge and perspectives

K Wdowiak, T Francuz, E Gallego-Colon… - International journal of …, 2018 - mdpi.com
The incidence and mortality of cancer have increased over the past decades. Significant
progress has been made in understanding the underpinnings of this disease and …

[HTML][HTML] Galectins in cancer: carcinogenesis, diagnosis and therapy

AH Ebrahim, Z Alalawi, L Mirandola… - Annals of …, 2014 - ncbi.nlm.nih.gov
A major breakthrough in the field of medical oncology has been the discovery of galectins
and their role in cancer development, progression and metastasis. In this review article we …

Glycan changes: cancer metastasis and anti-cancer vaccines

M Li, L Song, X Qin - Journal of biosciences, 2010 - Springer
Complex carbohydrates, which are major components of the cell membrane, perform
important functions in cell-cell and cell-extracellular matrix interactions, as well as in signal …

Placental galectins in cancer: why we should pay more attention

C Fuselier, A Dumoulin, A Paré, R Nehmé, S Ajarrag… - Cells, 2023 - mdpi.com
The first studies suggesting that abnormal expression of galectins is associated with cancer
were published more than 30 years ago. Today, the role of galectins in cancer is relatively …

Intracellular galectins in cancer cells: potential new targets for therapy

MC Vladoiu, M Labrie… - … journal of oncology, 2014 - spandidos-publications.com
Dysregulation of galectin expression is frequently observed in cancer tissues. Such an
abnormal expression pattern often correlates with aggressiveness and relapse in many …

KIT Mutations Correlate with Higher Galectin Levels and Brain Metastasis in Breast and Non-Small Cell Lung Cancer

AT Funkhouser, AM Strigenz, BB Blair, AP Miller… - Cancers, 2022 - mdpi.com
Simple Summary Galectins are a family of β-galactoside binding proteins whose levels are
altered in various stages of different types of cancer. This study provides an analytical …