Automatic human sleep stage scoring using deep neural networks

A Malafeev, D Laptev, S Bauer, X Omlin… - Frontiers in …, 2018 - frontiersin.org
The classification of sleep stages is the first and an important step in the quantitative
analysis of polysomnographic recordings. Sleep stage scoring relies heavily on visual …

Sleep scoring in rodents: Criteria, automatic approaches and outstanding issues

A Rayan, A Agarwal, A Samanta… - European Journal of …, 2024 - Wiley Online Library
There is nothing we spend as much time on in our lives as we do sleeping, which makes it
even more surprising that we currently do not know why we need to sleep. Most of the …

Distinct phosphorylation states of mammalian CaMKIIβ control the induction and maintenance of sleep

D Tone, KL Ode, Q Zhang, H Fujishima… - PLoS …, 2022 - journals.plos.org
The reduced sleep duration previously observed in Camk2b knockout mice revealed a role
for Ca2+/calmodulin-dependent protein kinase II (CaMKII) β as a sleep-promoting kinase …

Muscarinic acetylcholine receptors Chrm1 and Chrm3 are essential for REM sleep

Y Niwa, GN Kanda, RG Yamada, S Shi, GA Sunagawa… - Cell Reports, 2018 - cell.com
Sleep regulation involves interdependent signaling among specialized neurons in
distributed brain regions. Although acetylcholine promotes wakefulness and rapid eye …

Prefrontal synaptic regulation of homeostatic sleep pressure revealed through synaptic chemogenetics

T Sawada, Y Iino, K Yoshida, H Okazaki, S Nomura… - Science, 2024 - science.org
Sleep is regulated by homeostatic processes, yet the biological basis of sleep pressure that
accumulates during wakefulness, triggers sleep, and dissipates during sleep remains …

Mammalian reverse genetics without crossing reveals Nr3a as a short-sleeper gene

GA Sunagawa, K Sumiyama, M Ukai-Tadenuma… - Cell reports, 2016 - cell.com
The identification of molecular networks at the system level in mammals is accelerated by
next-generation mammalian genetics without crossing, which requires both the efficient …

Endocannabinoid signaling regulates sleep stability

MJ Pava, A Makriyannis, DM Lovinger - PLoS One, 2016 - journals.plos.org
The hypnogenic properties of cannabis have been recognized for centuries, but
endogenous cannabinoid (endocannabinoid) regulation of vigilance states is poorly …

SPINDLE: End-to-end learning from EEG/EMG to extrapolate animal sleep scoring across experimental settings, labs and species

Đ Miladinović, C Muheim, S Bauer… - PLoS computational …, 2019 - journals.plos.org
Understanding sleep and its perturbation by environment, mutation, or medication remains a
central problem in biomedical research. Its examination in animal models rests on brain …

Assessing environmental gradients in relation to dark CO2 fixation in estuarine wetland microbiomes

L Grüterich, JN Woodhouse, P Mueller… - Applied and …, 2024 - journals.asm.org
The rising atmospheric concentration of CO2 is a major concern to society due to its global
warming potential. In soils, CO2-fixing microorganisms are preventing some of the CO2 from …

MC-SleepNet: large-scale sleep stage scoring in mice by deep neural networks

M Yamabe, K Horie, H Shiokawa, H Funato… - Scientific reports, 2019 - nature.com
Automated sleep stage scoring for mice is in high demand for sleep research, since manual
scoring requires considerable human expertise and efforts. The existing automated scoring …