Bacterial defences: mechanisms, evolution and antimicrobial resistance

WPJ Smith, BR Wucher, CD Nadell… - Nature Reviews …, 2023 - nature.com
Throughout their evolutionary history, bacteria have faced diverse threats from other
microorganisms, including competing bacteria, bacteriophages and predators. In response …

[HTML][HTML] Antibiotic resistance in microbes: History, mechanisms, therapeutic strategies and future prospects

TM Uddin, AJ Chakraborty, A Khusro… - Journal of infection and …, 2021 - Elsevier
Antibiotics have been used to cure bacterial infections for more than 70 years, and these low-
molecular-weight bioactive agents have also been used for a variety of other medicinal …

The global preclinical antibacterial pipeline

U Theuretzbacher, K Outterson, A Engel… - Nature Reviews …, 2020 - nature.com
Antibacterial resistance is a great concern and requires global action. A critical question is
whether enough new antibacterial drugs are being discovered and developed. A review of …

Antibiotic resistance genes from livestock waste: occurrence, dissemination, and treatment

Y He, Q Yuan, J Mathieu, L Stadler, N Senehi, R Sun… - NPJ Clean …, 2020 - nature.com
Antibiotics are widely used in animal husbandry, and various types of antibiotic resistance
genes (ARGs) are frequently detected in livestock waste around the world. Conventional …

Mode-of-action of antimicrobial peptides: membrane disruption vs. intracellular mechanisms

AH Benfield, ST Henriques - Frontiers in Medical Technology, 2020 - frontiersin.org
Antimicrobial peptides are an attractive alternative to traditional antibiotics, due to their
physicochemical properties, activity toward a broad spectrum of bacteria, and mode-of …

Recent innovations in bacterial infection detection and treatment

C Deusenbery, Y Wang, A Shukla - ACS Infectious Diseases, 2021 - ACS Publications
Bacterial infections are a major threat to human health, exacerbated by increasing antibiotic
resistance. These infections can result in tremendous morbidity and mortality, emphasizing …

Quaternized carbon quantum dots with broad-spectrum antibacterial activity for the treatment of wounds infected with mixed bacteria

C Zhao, X Wang, L Yu, L Wu, X Hao, Q Liu, L Lin… - Acta Biomaterialia, 2022 - Elsevier
Bacterial resistance to antibiotics have become one of the most severe threats in global
public health, so the development of new-style antimicrobial agents is urgent. In this work …

Dissemination of antibiotic resistance genes (ARGs) via integrons in Escherichia coli: a risk to human health

S Zhang, M Abbas, MU Rehman, Y Huang, R Zhou… - Environmental …, 2020 - Elsevier
With the induction of various emerging environmental contaminants such as antibiotic
resistance genes (ARGs), environment is considered as a key indicator for the spread of …

Combating food spoilage and pathogenic microbes via bacteriocins: A natural and eco-friendly substitute to antibiotics

M Nisa, RA Dar, BA Fomda, R Nazir - Food Control, 2023 - Elsevier
Food and aquaculture industries are at risk from pathogenic bacteria. Pathogenic bacteria
can contaminate food at any step in the supply chain and cause huge damage to both the …

Development of Membrane-Active Honokiol/Magnolol Amphiphiles as Potent Antibacterial Agents against Methicillin-Resistant Staphylococcus aureus (MRSA)

Y Guo, E Hou, T Wen, X Yan, M Han… - Journal of medicinal …, 2021 - ACS Publications
Currently, infections caused by drug-resistant bacteria have become a new challenge in anti-
infective treatment, seriously endangering public health. In our continuous effort to develop …