CD4+ CD25+ regulatory T (Treg) cells play a pivotal role in the maintenance of immune
homeostasis, where the X-linked master transcription factor forkhead box P3 (FOXP3) …

The gut barrier is a single cell layer that separates gut micro-organisms from the host, and
gut permeability defects result in the translocation of microbial molecules from the gut into …

Aim To determine the role of IL-17 and IL-6 in the pathogenesis of SLE as biomarkers of
disease activity and predictors of remission and outcome of therapy in patients with active …

Systemic lupus erythematosus (SLE) is a type of autoimmune disease that damages multiple
organs, including the heart, joints, liver and kidneys. The main characteristics of SLE are the …

Objectives While patients with systemic lupus erythematosus (SLE) have poorer health-
related quality of life (HRQoL) and are more depressed than healthy people, the impact of …

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by chronic
inflammation. This study sought to assess the effects of an exercise training program on …

Tumour necrosis factor-α (TNF-α) plays a major role in propagating the inflammatory
processes responsible for tissue damage in systemic lupus erythematosus (SLE) and is …

AIM OF THE STUDY: Radix Bupleuri, one of the most frequently prescribed crude herbs in
traditional Chinese medicine, has been used for centuries to treat inflammatory diseases …

Background Lupus nephritis (LN) is a chronic autoimmune disease, leading to progressive
renal dysfunction. MicroRNAs (miRNAs) contribute to LN pathophysiology. Nevertheless, the …

OBJECTIVE: To determine the serum levels of Th1 (IL-12, IFN-γ, TNF-α) and Th2 (IL-5, IL-6
and IL-10) cytokines in childhood-onset SLE, first-degree relatives and healthy controls. To …