Importance Novel treatments for opioid use disorder (OUD) are needed to address both the
ongoing opioid epidemic and long-standing barriers to existing OUD treatments that target …

Rationale Synthetic opioids like fentanyl are contributing to the rise in rates of opioid use
disorder and drug overdose deaths. Sleep dysfunction and circadian rhythm disruption may …

Addiction is a multifaceted health challenge with profound consequences for both
individuals who experience addiction and society at large. This chapter explores addiction …

Opioid drugs are the most effective tools for treating moderate to severe pain. Despite their
analgesic efficacy, long-term opioid use can lead to drug tolerance, addiction, and …

Introduction Use of conventional cigarettes (CIG), alcohol, marijuana, and sedatives [ie,
benzodiazepines and barbiturates]) commonly co-occur with internalizing and externalizing …

This article addresses the issue of patient sleep during hospitalization, which the Society of
Anesthesia and Sleep Medicine believes merits wider consideration by health authorities …

Opioids like fentanyl remain the mainstay treatment for chronic pain. Unfortunately, opioid's
high dependence liability has led to the current opioid crisis, in part, because of side‐effects …

Introduction In the current opioid crisis, bariatric surgical patients are at increased risk of
harms related to postoperative opioid overprescribing. This study aimed to assess the extent …

Opioid transport into the central nervous system is crucial for the analgesic efficacy of opioid
drugs. Thus, the pharmacokinetics of opioid analgesics such as morphine have been …

Background Recent studies have proposed the use of dual orexin receptor antagonists,
such as suvorexant, for the treatment of opioid use disorder (OUD) and opioid-related sleep …