Psychotic syndromes can be understood as disorders of adaptation to social context.
Although heritability is often emphasized, onset is associated with environmental factors …

During the last decades, schizophrenia has been regarded as a developmental disorder.
The neurodevelopmental hypothesis proposes schizophrenia to be related to genetic and …

Rationale The birth of neurons, their migration to appropriate positions in the brain, and their
establishment of the proper synaptic contacts happen predominately during the prenatal …

The term allostasis, which is defined as stability through change, has been invoked
repeatedly by developmental psychopathologists to describe long-lasting and in some …

We have previously shown that male rats exposed to gestational stress exhibit phenotypes
resembling what is observed in schizophrenia, including hypersensitivity to amphetamine …

Abstract Aims: Docosahexaenoic acid (22: 6n-3; DHA) is known to play a critical role in
postnatal brain development. However, no study has been performed to investigate its …

There is a large consensus that the prenatal environment determines the susceptibility to
pathological conditions later in life. The hypothesis most widely accepted is that exposure to …

Adverse early life events are a well-established risk factor for the precipitation of behavioral
disorders characterized by anomalies in the dopaminergic system, such as schizophrenia …

Depression may be associated with reduced monoamine neurotransmission, particularly
serotonin and norepinephrine (NE). Reuptake of NE by the norepinephrine transporter …

Prenatal stress (PS) impacts early postnatal behavioural and cognitive development. This
process of 'fetal programming'is mediated by the effects of the prenatal experience on the …