Pyridines and pyrimidines are the class of heterocyclic nitrogenous compounds having
plethora of applications in anticancer drug development. These synthetic sources serve as …

Heterocyclic derivatives as a major group of organic compounds are enormously used for a
wide range of pharmaceutical and industrial applications. They are known for their biological …

Pyrazole derivatives, as a class of heterocyclic compounds, possess unique chemical
structures that confer them with a broad spectrum of pharmacological activities. They have …

Pyrazolopyrimidine scaffold is one of the privileged heterocycles in drug discovery. This
scaffold produced numerous biological activities in which anticancer is important one …

One concept of improving anticancer effects of conventional platinum‐based antitumor
drugs consists of conjugating these compounds with other biologically (antitumor) active …

Mercury is considered as a highly toxic metal ion due to its lethal effects on humans and the
ecological system. The increasing level of antimicrobial resistance are threatening to the …

Cancer is the world's biggest global health concern. The prevalence and mortality rates of
cancer remain high despite significant progress in cancer therapy. The search for more …

Among the menacing diseases, cancer needs the most attention as millions of people are
affected by it worldwide. Genetic and environmental factors play a pivotal role in causing …

Abstract Kinesin Family Member 15 (KIF15) is a plus end-directed microtubule motor, which
exerts complex regulations in cancer biology. This study aimed to explore the functional role …

Regardless of the growing discovery of anticancer treatments targeting cancer-specific
pathways, cytotoxic therapy still maintained its abundant clinical significance because …