BACKGROUND Environmental, geopolitical, and economic factors are reshaping our view
of global energy and manufacturing demands. Addressing these challenges may require a …

Probiotics, live microorganisms that, when administered in adequate amounts, confer a
health benefit on the host, offer an alternative to antibiotics and have become popular …

We present a whole-cell fully dynamical kinetic model (WCM) of JCVI-syn3A, a minimal cell
with a reduced genome of 493 genes that has retained few regulatory proteins or small …

Abstract eQuilibrator (equilibrator. weizmann. ac. il) is a database of biochemical equilibrium
constants and Gibbs free energies, originally designed as a web-based interface. While the …

Overflow metabolism refers to the seemingly wasteful strategy in which cells use
fermentation instead of the more efficient respiration to generate energy, despite the …

In metabolism, available free energy is limited and must be divided across pathway steps to
maintain a negative Δ G throughout. For each reaction, Δ G is log proportional both to a …

Metabolic exchange mediates interactions among microbes, helping explain diversity in
microbial communities. As these interactions often involve a fitness cost, it is unclear how …

Abstract Marine Rhodobacteraceae (Alphaproteobacteria) are key players of
biogeochemical cycling, comprise up to 30% of bacterial communities in pelagic …

Metabolic efficiency profoundly influences organismal fitness. Nonphotosynthetic organisms,
from yeast to mammals, derive usable energy primarily through glycolysis and respiration …

SAR11 is a group of small, carbon-oxidizing bacteria that reach a global estimated
population size of 2.4× 1028 cells—approximately 25% of all plankton. They are found …