Targeting angiogenesis in breast cancer: current evidence and future perspectives of novel anti-angiogenic approaches
NM Ayoub, SK Jaradat, KM Al-Shami… - Frontiers in …, 2022 - frontiersin.org
Angiogenesis is a vital process for the growth and dissemination of solid cancers. Numerous
molecular pathways are known to drive angiogenic switch in cancer cells promoting the …
molecular pathways are known to drive angiogenic switch in cancer cells promoting the …
Tumor angiogenesis revisited: regulators and clinical implications
Abstract Since Judah Folkman hypothesized in 1971 that angiogenesis is required for solid
tumor growth, numerous studies have been conducted to unravel the angiogenesis process …
tumor growth, numerous studies have been conducted to unravel the angiogenesis process …
[HTML][HTML] Exosomal lncRNA-H19 promotes osteogenesis and angiogenesis through mediating Angpt1/Tie2-NO signaling in CBS-heterozygous mice
Rationale: Emerging evidence indicates that the growth of blood vessels and osteogenesis
is tightly coordinated during bone development. However, the molecular regulators of …
is tightly coordinated during bone development. However, the molecular regulators of …
Tumor suppressor miRNA-204-5p regulates growth, metastasis, and immune microenvironment remodeling in breast cancer
Various miRNAs play critical roles in the development and progression of solid tumors. In
this study, we describe the role of miR-204-5p in limiting growth and progression of breast …
this study, we describe the role of miR-204-5p in limiting growth and progression of breast …
New insights into the regulatory role of microRNA in tumor angiogenesis and clinical implications
Y Wang, L Wang, C Chen, X Chu - Molecular cancer, 2018 - Springer
Angiogenesis is essential for tumor growth and metastasis. Understanding the regulation of
tumor angiogenesis has become increasingly important. MicroRNAs (miRNAs) are small …
tumor angiogenesis has become increasingly important. MicroRNAs (miRNAs) are small …
MicroRNA‐204‐5p: A pivotal tumor suppressor
MicroRNAs (miRNAs) are a class of non‐coding single‐stranded RNA molecules with a
length of approximately 18‐25 nt nucleotides that regulate gene expression post …
length of approximately 18‐25 nt nucleotides that regulate gene expression post …
DSCAM‐AS1 promotes tumor growth of breast cancer by reducing miR‐204‐5p and up‐regulating RRM2
WH Liang, N Li, ZQ Yuan, XL Qian… - Molecular …, 2019 - Wiley Online Library
Breast cancer (BC) is a common malignancy worldwide. More than 3 700 000 women die of
BC every year. DSCAM‐AS1 was overexpressed several kinds of cancer and miR‐204‐5p …
BC every year. DSCAM‐AS1 was overexpressed several kinds of cancer and miR‐204‐5p …
Effects of metformin and phenformin on apoptosis and epithelial‐mesenchymal transition in chemoresistant rectal cancer
JH Park, Y Kim, EH Park, SJ Lee, H Kim, A Kim… - Cancer …, 2019 - Wiley Online Library
Recurrence and chemoresistance in colorectal cancer remain important issues for patients
treated with conventional therapeutics. Metformin and phenformin, previously used in the …
treated with conventional therapeutics. Metformin and phenformin, previously used in the …
Non-coding RNAs as potential therapeutic targets in breast cancer
Paradigm shifting studies especially involving non-coding RNAs (ncRNAs) during last few
decades have significantly changed the scientific perspectives regarding the complexity of …
decades have significantly changed the scientific perspectives regarding the complexity of …
microRNAs orchestrate pathophysiology of breast cancer brain metastasis: advances in therapy
Brain metastasis (BM) predominantly occurs in triple-negative (TN) and epidermal growth
factor 2 (HER2)-positive breast cancer (BC) patients, and currently, there is an unmet need …
factor 2 (HER2)-positive breast cancer (BC) patients, and currently, there is an unmet need …