Transient receptor potential canonical (TRPC) channels: then and now

X Chen, G Sooch, IS Demaree, FA White, AG Obukhov - Cells, 2020 - mdpi.com
Twenty-five years ago, the first mammalian Transient Receptor Potential Canonical (TRPC)
channel was cloned, opening the vast horizon of the TRPC field. Today, we know that there …

TRP channels

K Venkatachalam, C Montell - Annu. Rev. Biochem., 2007 - annualreviews.org
Abstract The TRP (Transient Receptor Potential) superfamily of cation channels is
remarkable in that it displays greater diversity in activation mechanisms and selectivities …

The TRP superfamily of cation channels

C Montell - Science's STKE, 2005 - science.org
The transient receptor potential (TRP) protein superfamily consists of a diverse group of
cation channels that bear structural similarities to Drosophila TRP. TRP channels play …

Store depletion and calcium influx

AB Parekh, R Penner - Physiological reviews, 1997 - journals.physiology.org
Calcium influx in nonexcitable cells regulates such diverse processes as exocytosis,
contraction, enzyme control, gene regulation, cell proliferation, and apoptosis. The dominant …

OSM-9, A novel protein with structural similarity to channels, is required for olfaction, mechanosensation, and olfactory adaptation incaenorhabditis elegans

HA Colbert, TL Smith, CI Bargmann - Journal of Neuroscience, 1997 - Soc Neuroscience
Although cyclic nucleotide-gated channels mediate sensory transduction in olfaction and
vision, other forms of sensory transduction are independent of these channels …

TRPC1 and TRPC5 form a novel cation channel in mammalian brain

C Strübing, G Krapivinsky, L Krapivinsky, DE Clapham - Neuron, 2001 - cell.com
TRP proteins are cation channels responding to receptor-dependent activation of
phospholipase C. Mammalian (TRPC) channels can form hetero-oligomeric channels in …

The TRPM7 channel is inactivated by PIP2 hydrolysis

LW Runnels, L Yue, DE Clapham - Nature cell biology, 2002 - nature.com
Abstract TRPM7 (ChaK1, TRP-PLIK, LTRPC7) is a ubiquitous, calcium-permeant ion
channel that is unique in being both an ion channel and a serine/threonine kinase. The …

Visual transduction in Drosophila

RC Hardie, P Raghu - Nature, 2001 - nature.com
The brain's capacity to analyse and interpret information is limited ultimately by the input it
receives. This sets a premium on information capacity of sensory receptors, which can be …

TRP channel proteins and signal transduction

B Minke, B Cook - Physiological reviews, 2002 - journals.physiology.org
TRP channel proteins constitute a large and diverse family of proteins that are expressed in
many tissues and cell types. This family was designated TRP because of a spontaneously …

Visual processing in the fly, from photoreceptors to behavior

TA Currier, MM Pang, TR Clandinin - Genetics, 2023 - academic.oup.com
Originally a genetic model organism, the experimental use of Drosophila melanogaster has
grown to include quantitative behavioral analyses, sophisticated perturbations of neuronal …