How to use biomarkers of infection or sepsis at the bedside: guide to clinicians

P Póvoa, L Coelho, F Dal-Pizzol, R Ferrer… - Intensive care …, 2023 - Springer
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to infection. In this context, biomarkers could be considered as indicators of either …

Ventilator-associated pneumonia: pathobiological heterogeneity and diagnostic challenges

F Howroyd, C Chacko, A MacDuff, N Gautam… - Nature …, 2024 - nature.com
Ventilator-associated pneumonia (VAP) affects up to 20% of critically ill patients and induces
significant antibiotic prescription pressure, accounting for half of all antibiotic use in the ICU …

International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia: Guidelines for the …

A Torres, MS Niederman, J Chastre… - European …, 2017 - Eur Respiratory Soc
The most recent European guidelines and task force reports on hospital-acquired
pneumonia (HAP) and ventilator-associated pneumonia (VAP) were published almost 10 …

The current status of biomarkers for the diagnosis of nosocomial pneumonias

JIF Salluh, VC Souza-Dantas… - Current opinion in critical …, 2017 - journals.lww.com
The evidence for the use of biomarkers to diagnose nosocomial pneumonia as a stand-
alone tool is low to moderate. Improved performance for both PCT and CRP can be obtained …

[HTML][HTML] Guidelines for the use of procalcitonin for rational use of antibiotics

GC Khilnani, P Tiwari, KG Zirpe… - Indian Journal of …, 2022 - ncbi.nlm.nih.gov
Guidelines for the Use of Procalcitonin for Rational Use of Antibiotics - PMC Back to Top Skip
to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main …

Procalcitonin in the assessment of ventilator associated pneumonia: a systematic review

F Alessandri, F Pugliese, S Angeletti… - … Infectious Diseases and …, 2021 - Springer
Background Ventilator-associated pneumonia (VAP) is one of the most common nosocomial
infection, associated with considerable mortality and morbidity in critically ill patients; …

Procalcitonin is not an independent predictor of 30-day mortality, albeit predicts pneumonia severity in patients with pneumonia acquired outside the hospital

T Akagi, N Nagata, H Miyazaki, T Harada, S Takeda… - BMC geriatrics, 2019 - Springer
Background Procalcitonin (PCT) is a useful marker for pneumonia. However, its clinical
usefulness in elderly patients has not been studied extensively. This study aimed to assess …

Serum procalcitonin as a biomarker for the prediction of bacterial exacerbation and mortality in severe COPD exacerbations requiring mechanical ventilation

B Ergan, AA Şahin, A Topeli - Respiration, 2016 - karger.com
Background: Procalcitonin (PCT) is being used as a marker of bacterial infections. Although
there are several studies showing the diagnostic yield of PCT to differentiate bacterial …

Significance of sTREM-1 in early prediction of ventilator-associated pneumonia in neonates: a single-center, prospective, observational study

X Zhao, L Xu, Z Yang, B Sun, Y Wang, G Li… - BMC Infectious …, 2020 - Springer
Background To evaluate whether soluble triggering receptor expressed on myeloid cells-1
(sTREM-1) can be used as an early predictor of ventilator-associated pneumonia (VAP) …

[HTML][HTML] Diagnostic and predictive values of procalcitonin in bloodstream infections for nosocomial pneumonia

ST Yan, LC Sun, R Lian, YK Tao, HB Zhang… - Journal of critical care, 2018 - Elsevier
Purpose We evaluated the diagnostic accuracy of PCT to distinguish between gram-
negative (GN) and gram-positive (GP) bloodstream infections nosocomial pneumonia (NP) …