For over 30 years, scientists have been investigating the phenomenon of pain suppression
upon exposure to unconditioned or conditioned stressful stimuli, commonly known as stress …

The amygdala is a structure of the temporal lobe thought to be involved in assigning
emotional significance to environmental information and triggering adapted physiological …

The lateral parabrachial nucleus (LPBN) is known to relay noxious information to the
amygdala for processing affective responses. However, it is unclear whether the LPBN …

Hunger and pain are two competing signals that individuals must resolve to ensure survival.
However, the neural processes that prioritize conflicting survival needs are poorly …

Hyperexcitability of the anterior cingulate cortex (ACC) is thought to drive aversion
associated with chronic neuropathic pain. Here, we studied the contribution of input from the …

This paper is the 28th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning over a quarter-century of research. It …

Dysfunction of glutamatergic synaptic plasticity in basolateral amygdala (BLA) constitutes a
critical pathogenic mechanism underlying the depression-like behaviors induced by chronic …

Neuroplasticity may be defined as the ability of the central nervous system (CNS) to respond
to changes in the internal and external environment and it is well established that some …

Neural circuits that control aversion are essential for motivational regulation and survival in
animals. The nucleus accumbens (NAc) plays an important role in predicting aversive …

Purpose Oncology patients receiving chemotherapy can experience both cancer and non-
cancer pain. In addition, oncology patients face numerous stressors and their responses are …