[HTML][HTML] Physiology of the endometrium and regulation of menstruation

HOD Critchley, JA Maybin… - Physiological …, 2020 - journals.physiology.org
The physiological functions of the uterine endometrium (uterine lining) are preparation for
implantation, maintenance of pregnancy if implantation occurs, and menstruation in the …

Endometrial immune dysfunction in recurrent pregnancy loss

C Ticconi, A Pietropolli, N Di Simone… - International journal of …, 2019 - mdpi.com
Recurrent pregnancy loss (RPL) represents an unresolved problem for contemporary
gynecology and obstetrics. In fact, it is not only a relevant complication of pregnancy, but is …

An integrated single-cell reference atlas of the human endometrium

M Marečková, L Garcia-Alonso, M Moullet, V Lorenzi… - Nature Genetics, 2024 - nature.com
The complex and dynamic cellular composition of the human endometrium remains poorly
understood. Previous endometrial single-cell atlases profiled few donors and lacked …

Histone acetylation and the role of histone deacetylases in normal cyclic endometrium

P Gujral, V Mahajan, AC Lissaman… - Reproductive Biology …, 2020 - Springer
Histone acetylation is a critical epigenetic modification that changes chromatin architecture
and regulates gene expression by opening or closing the chromatin structure. It plays an …

The role of epigenetic mechanisms in the regulation of gene expression in the cyclical endometrium

AM Retis-Resendiz, IN González-García… - Clinical …, 2021 - Springer
Background The human endometrium is a highly dynamic tissue whose function is mainly
regulated by the ovarian steroid hormones estradiol and progesterone. The serum levels of …

Oxidative Stress and the Nrf2/PPARγ Axis in the Endometrium: Insights into Female Fertility

P Artimovič, Z Badovská, S Toporcerová, I Špaková… - Cells, 2024 - mdpi.com
Successful pregnancy depends on precise molecular regulation of uterine physiology,
especially during the menstrual cycle. Deregulated oxidative stress (OS), often influenced by …

Metrosets: Visualizing sets as metro maps

B Jacobsen, M Wallinger, S Kobourov… - … on Visualization and …, 2020 - ieeexplore.ieee.org
We propose MetroSets, a new, flexible online tool for visualizing set systems using the metro
map metaphor. We model a given set system as a hypergraph, consisting of a set of vertices …

Notch signaling in reproduction

GE Moldovan, L Miele, AT Fazleabas - Trends in Endocrinology & …, 2021 - cell.com
The Notch signaling pathway is conserved among mammalian species and controls
proliferation, differentiation, and cell death in many organs throughout the body including the …

Does endometriosis influence the embryo quality and/or development? Insights from a large retrospective matched cohort study

AM Sanchez, L Pagliardini, GC Cermisoni, L Privitera… - Diagnostics, 2020 - mdpi.com
In vitro fertilization can be an effective tool to manage the endometriosis-associated
infertility, which accounts for 10% of the strategy indications. Nevertheless, a negative effect …

Killer timing: the temporal uterine natural killer cell differentiation pathway and implications for female reproductive health

R Fraser, AC Zenclussen - Frontiers in Endocrinology, 2022 - frontiersin.org
Natural killer (NK) cells are the predominant maternal uterine immune cell component, and
they densely populate uterine mucosa to promote key changes in the post-ovulatory …