The language of the protein universe

A Scaiewicz, M Levitt - Current opinion in genetics & development, 2015 - Elsevier
Proteins, the main cell machinery which play a major role in nearly every cellular process,
have always been a central focus in biology. We live in the post-genomic era, and inferring …

Reducing the impact of domain rearrangement on sequence alignment and phylogeny reconstruction

S Zaman, MS Bansal - International Symposium on Bioinformatics …, 2023 - Springer
Existing computational approaches for studying gene family evolution generally do not
account for domain rearrangement within gene families. However, it is well known that …

The BUBR1 pseudokinase domain promotes efficient kinetochore PP2A-B56 recruitment to regulate spindle checkpoint silencing and chromosome alignment

LG Braga, AF Cisneros, M Mathieu, M Clerc, P Garcia… - bioRxiv, 2019 - biorxiv.org
The balance of phospho-signalling at outer-kinetochores during mitosis is critical for the
accurate attachments between kinetochores and the mitotic spindle and timely exit from …

[PDF][PDF] Multiple Sequence Alignment with R/submitted by Dipl.-Inf. Enrico Bonatesta; Mag. Dipl.-Ing. Christoph Horejš-Kainrath

E Bonatesta, C Horejš-Kainrath - 2016 - epub.jku.at
Multiple Sequence Alignment with R Page 1 Submitted by Dipl.-Inf. Enrico Bonatesta Mag.
Dipl.-Ing. Christoph Horejš-Kainrath Submitted at Institute for Bioinformatics Supervisor …

Origem de genes recentes, uma abordagem com PSSMs deterioradas e arquiteturas de domínio proteico

DT Souza - 2016 - teses.usp.br
A origem dos novos genes é um processo importante para a evolução dos organismos, pois
ela fornece fontes singulares para a inovação evolutiva. As abordagens que mostram como …

[引用][C] Andrea Scaiewicz

M Levitt - Curr Opin Genet Dev