Prognostic biomarkers in oral squamous cell carcinoma: a systematic review

C Rivera, AK Oliveira, RAP Costa, T De Rossi… - Oral oncology, 2017 - Elsevier
Over the years, several tumor biomarkers have been suggested to foresee the prognosis
oral squamous cell carcinoma (OSCC) patients. Here, we present a systematic review to …

Tissue biomarkers for predicting the risk of oral cancer in patients diagnosed with oral leukoplakia: A systematic review

L Monteiro, FW Mello, S Warnakulasuriya - Oral Diseases, 2021 - Wiley Online Library
Objectives We performed a systematic review to evaluate the published biomarkers related
to oral leukoplakia (OL), aiming to identify the biomarkers that indicate any future risk of …

Significance of p53 overexpression in the prediction of the malignant transformation risk of oral potentially malignant disorders: A systematic review and meta-analysis

P Ramos-Garcia, MA Gonzalez-Moles… - Oral oncology, 2022 - Elsevier
Objectives To evaluate the current evidence in relation to the predictive value of p53
overexpression as a biomarker of the malignant transformation risk in oral potentially …

Malignant transformation rate of oral leukoplakia in the past 20 years: A systematic review and meta‐analysis

JY Guan, YH Luo, YY Lin, ZY Wu, JY Ye… - Journal of Oral …, 2023 - Wiley Online Library
Background This meta‐analysis aimed to assess the rate of malignant transformation (MT) of
oral leukoplakia (OL) and to study potential risk factors for the MT of OL into oral squamous …

Prognostic Relevance of CD4+, CD8+ and FOXP3+ TILs in Oral Squamous Cell Carcinoma and Correlations with PD-L1 and Cancer Stem Cell Markers

P Lequerica-Fernández, J Suárez-Canto… - Biomedicines, 2021 - mdpi.com
This study investigates the relevance of tumor-infiltrating lymphocytes (TILs) in oral
squamous cell carcinoma (OSCC). Immunohistochemical analysis of stromal/tumoral CD4+ …

World Workshop on Oral Medicine VII: Prognostic biomarkers in oral leukoplakia and proliferative verrucous leukoplakia—A systematic review of retrospective studies

A Celentano, I Glurich, WS Borgnakke… - Oral …, 2021 - Wiley Online Library
Objective To systematically review retrospective studies examining prognostic potentials of
candidate biomarkers to stratify malignant progression of oral leukoplakia (OL) and …

Podoplanin emerges as a functionally relevant oral cancer biomarker and therapeutic target

EP Retzbach, SA Sheehan, EM Nevel, A Batra, T Phi… - Oral oncology, 2018 - Elsevier
Oral cancer has become one of the most aggressive types of cancer, killing 140,000 people
worldwide every year. Current treatments for oral cancer include surgery and radiation …

Oral potentially malignant disorders: A scoping review of prognostic biomarkers

FW Mello, G Melo, ENS Guerra… - Critical Reviews in …, 2020 - Elsevier
This scoping review aimed to map evidence regarding biomarkers for malignant
transformation of oral potentially malignant disorders (OPMD). Seventy-three longitudinal …

Podoplanin—a novel marker in oral carcinogenesis

N Swain, SV Kumar, S Routray, J Pathak, S Patel - Tumor Biology, 2014 - Springer
Podoplanin, a transmembrane sialoglycoprotein, is a specific marker for lymphatic
endothelial cells which in recent years has gained prominent notoriety for its role in tumor …

The emerging role of NANOG as an early cancer risk biomarker in patients with oral potentially malignant disorders

JC de Vicente, T Rodríguez-Santamarta… - Journal of clinical …, 2019 - mdpi.com
NANOG, a key regulator of pluripotency and self-renewal in embryonic and adult stem cells,
is frequently overexpressed in multiple cancers, including oral squamous cell carcinoma …