Materials for the spine: anatomy, problems, and solutions
Disc degeneration affects 12% to 35% of a given population, based on genetics, age,
gender, and other environmental factors, and usually occurs in the lumbar spine due to …
gender, and other environmental factors, and usually occurs in the lumbar spine due to …
Role of biomechanics in intervertebral disc degeneration and regenerative therapies: what needs repairing in the disc and what are promising biomaterials for its …
BACKGROUND CONTEXT: Degeneration and injuries of the intervertebral disc (IVD) result
in large alterations in biomechanical behaviors. Repair strategies using biomaterials can be …
in large alterations in biomechanical behaviors. Repair strategies using biomaterials can be …
Measurements of proteoglycan and water content distribution in human lumbar intervertebral discs
JC Iatridis, JJ MacLean, M O'Brien, IAF Stokes - Spine, 2007 - journals.lww.com
Study Design. Study of regional variations in composition in a sample of 9 mildly to
moderately degenerated human intervertebral discs. Objective. The aim of this study was to …
moderately degenerated human intervertebral discs. Objective. The aim of this study was to …
Poly (vinyl alcohol) cryogels for biomedical applications
W Wan, AD Bannerman, L Yang, H Mak - … cryogels: macroporous gels with …, 2014 - Springer
Abstract Poly (vinyl alcohol)(PVA) is a hydrophilic and biocompatible polymer that can be
crosslinked to form a hydrogel. When physically crosslinked using a freeze–thaw cycling …
crosslinked to form a hydrogel. When physically crosslinked using a freeze–thaw cycling …
Elastic, permeability and swelling properties of human intervertebral disc tissues: A benchmark for tissue engineering
The aim of functional tissue engineering is to repair and replace tissues that have a
biomechanical function, ie, connective orthopaedic tissues. To do this, it is necessary to …
biomechanical function, ie, connective orthopaedic tissues. To do this, it is necessary to …
Image-guided tissue engineering of anatomically shaped implants via MRI and micro-CT using injection molding
JJ Ballyns, JP Gleghorn, V Niebrzydowski… - … Engineering Part A, 2008 - liebertpub.com
This study demonstrates for the first time the development of engineered tissues based on
anatomic geometries derived from widely used medical imaging modalities such as …
anatomic geometries derived from widely used medical imaging modalities such as …
Effect of hydration on healthy intervertebral disk mechanical stiffness
The intervertebral disk has an excellent swelling capacity to absorb water, which is thought
to be largely due to the high proteoglycan composition. Injury, aging, degeneration, and …
to be largely due to the high proteoglycan composition. Injury, aging, degeneration, and …
Dynamic compressive behavior of human meniscus correlates with its extra-cellular matrix composition
P Bursac, S Arnoczky, A York - Biorheology, 2009 - content.iospress.com
The menisci of the knee play a significant role in the complex biomechanics of the joint and
are critically important in maintaining articular cartilage health. While a general form …
are critically important in maintaining articular cartilage health. While a general form …
Localized intervertebral disc injury leads to organ level changes in structure, cellularity, and biosynthesis
A literature review and new data are presented to evaluate the influence of intervertebral
disc (IVD) injury on biomechanics, cellularity, inflammation, and biosynthesis. Literature and …
disc (IVD) injury on biomechanics, cellularity, inflammation, and biosynthesis. Literature and …
Anisotropic hydraulic permeability under finite deformation
GA Ateshian, JA Weiss - 2010 - asmedigitalcollection.asme.org
The structural organization of biological tissues and cells often produces anisotropic
transport properties. These tissues may also undergo large deformations under normal …
transport properties. These tissues may also undergo large deformations under normal …