Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing

JK Joung, JD Sander, M Maeder, Y Fu - US Patent 9,567,604, 2017 - Google Patents
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Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing

JK Joung, S Tsai - US Patent 9,567,603, 2017 - Google Patents
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Increasing specificity for RNA-guided genome editing

JK Joung, J Angstman, JD Sander, M Maeder… - US Patent …, 2018 - Google Patents
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US9885033B2 - Increasing specificity for RNA-guided genome editing - Google Patents …

RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci

JK Joung, M Maeder - US Patent 10,760,064, 2020 - Google Patents
BACKGROUND Clustered Regulatory Interspaced Short Palindromic Repeats (CRISPR),
and CRISPR-associated (cas) genes, referred to as CRISPR/Cas systems, are used by …

Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing

JK Joung, JD Sander, Y Fu, M Maeder - US Patent 10,119,133, 2018 - Google Patents
CRISPR-Cas genome editing uses a guide RNA, which includes both a complementarity
region, which binds the target DNA by base-pairing, and a Cas9-binding region, to direct a …

RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci

JK Joung, M Maeder - US Patent 10,378,027, 2019 - Google Patents
US10378027B2 - RNA-guided targeting of genetic and epigenomic regulatory proteins to
specific genomic loci - Google Patents US10378027B2 - RNA-guided targeting of genetic …

Engineered CRISPR-Cas9 nucleases

JK Joung, B Kleinstiver, V Pattanayak - US Patent 9,512,446, 2016 - Google Patents
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Engineered CRISPR-Cas9 nucleases

JK Joung, B Kleinstiver, V Pattanayak - US Patent 9,926,546, 2018 - Google Patents
US9926546B2 - Engineered CRISPR-Cas9 nucleases - Google Patents US9926546B2 -
Engineered CRISPR-Cas9 nucleases - Google Patents Engineered CRISPR-Cas9 nucleases …

Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing

JK Joung, S Tsai - US Patent 10,138,476, 2018 - Google Patents
US10138476B2 - Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided
genome editing - Google Patents US10138476B2 - Using RNA-guided FokI nucleases (RFNs) …

Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing

JK Joung, JD Sander, M Maeder, Y Fu - US Patent 10,415,059, 2019 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
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