[HTML][HTML] Recent developments in lactose blend formulations for carrier-based dry powder inhalation

GA Hebbink, M Jaspers, HJW Peters… - Advanced Drug Delivery …, 2022 - Elsevier
Lactose is the most commonly used excipient in carrier-based dry powder inhalation (DPI)
formulations. Numerous inhalation therapies have been developed using lactose as a …

[HTML][HTML] Particle engineering in dry powders for inhalation

R Scherließ, S Bock, N Bungert, A Neustock… - European Journal of …, 2022 - Elsevier
Drug administration by inhalation is a well-established approach to treat respiratory and
systemic diseases. To deliver a drug into the lung dry powder inhalation (DPI) is an …

[HTML][HTML] Pharmaceutical approaches on antimicrobial resistance: prospects and challenges

F Nainu, AD Permana, NJN Djide, QK Anjani… - Antibiotics, 2021 - mdpi.com
The rapid increase in pathogenic microorganisms with antimicrobial resistant profiles has
become a significant public health problem globally. The management of this issue using …

Advances in the treatment of atherosclerosis with ligand‐modified nanocarriers

X Deng, J Wang, S Yu, S Tan, T Yu, Q Xu, N Chen… - …, 2024 - Wiley Online Library
Atherosclerosis, a chronic disease associated with metabolism, poses a significant risk to
human well‐being. Currently, existing treatments for atherosclerosis lack sufficient efficiency …

Drug combinations for inhalation: Current products and future development addressing disease control and patient compliance

H Banat, R Ambrus, I Csóka - International Journal of Pharmaceutics, 2023 - Elsevier
Pulmonary delivery is an alternative route of administration with numerous advantages over
conventional routes of administration. It provides low enzymatic exposure, fewer systemic …

Dry powder inhalers of antitubercular drugs

N Nainwal, Y Sharma, V Jakhmola - Tuberculosis, 2022 - Elsevier
Despite advancements in the medical and pharmaceutical fields, tuberculosis remains a
major health problem globally. Patients do not widely accept the conventional approach to …

[HTML][HTML] Advancements in chitosan-based nanoparticles for pulmonary drug delivery

TM Zacaron, MLS Silva, MP Costa, DM Silva, AC Silva… - Polymers, 2023 - mdpi.com
The evolution of respiratory diseases represents a considerable public health challenge, as
they are among the leading causes of death worldwide. In this sense, in addition to the high …

A quality-by-design strategic approach for the development of bedaquiline-pretomanid nanoparticles as inhalable dry powders for TB treatment

SM Patil, AM Diorio, P Kommarajula… - International Journal of …, 2024 - Elsevier
Tuberculosis (TB) is caused by Mycobacterium tuberculosis (M. tb) and is the second
leading cause of death from an infectious disease globally. The disease mainly affects the …

Flow cytometric analysis, confocal laser scanning microscopic, and holotomographic imaging demonstrate potentials of levofloxacin dry powder aerosols for TB …

T Srichana, E Thawithong, T Nakpheng… - Journal of Drug Delivery …, 2023 - Elsevier
Levofloxacin-proliposomes comprised of cholesterol, cholesterol sulfate, the core carrier
mannitol, ammonium acetate, trehalose, and leucine prepared by the spray drying technique …

[HTML][HTML] Efficacy and Safety of Dry Powder Antibiotics: A Narrative Review

D de la Rosa-Carrillo, G Suárez-Cuartín… - Journal of Clinical …, 2023 - mdpi.com
The use of inhaled antibiotics was initially almost exclusively confined to patients with cystic
fibrosis (CF). However, it has been extended in recent decades to patients with non-CF …