Understanding and harnessing triple-negative breast cancer-related microbiota in oncology

C Devoy, Y Flores Bueso, M Tangney - Frontiers in Oncology, 2022 - frontiersin.org
Bacterial inhabitants of the body have the potential to play a role in various stages of cancer
initiation, progression, and treatment. These bacteria may be distal to the primary tumour …

Microbiome analysis from formalin-fixed paraffin-embedded tissues: current challenges and future perspectives

R Cruz-Flores, JA López-Carvallo… - Journal of …, 2022 - Elsevier
Formalin-fixed paraffin-embedded (FFPE) tissues stored in thousands of human and animal
pathology laboratories around the globe represent mines of stored genetic information. In …

Intratumoral microbiome of human primary liver cancer

D Qu, Y Wang, Q Xia, J Chang, X Jiang… - Hepatology …, 2022 - journals.lww.com
Primary liver tumors (PLCs) and liver metastasis currently represent the leading cause of
cancer‐related deaths worldwide due to poor outcomes, high incidence, and postsurgical …

Identification of potential genomic alterations and the circRNA-miRNA-mRNA regulatory network in primary and recurrent synovial sarcomas

Q Yao, YL He, N Wang, SS Dong… - Frontiers in Molecular …, 2021 - frontiersin.org
Introduction: Synovial sarcoma (SS) is one of the most invasive soft tissue sarcomas, prone
to recurrence and metastasis, and the efficacy of surgical treatment and chemotherapy for …

Formalin-Fixed Paraffin-Embedded (FFPE) samples are not a beneficial replacement for frozen tissues in fetal membrane microbiota research

R Hockney, CH Orr, GJ Waring, I Christiaens… - PLoS …, 2022 - journals.plos.org
Formalin-Fixed Paraffin-Embedded (FFPE) tissues are routinely collected, archived, and
used for clinical diagnosis, including maternal and neonatal health. Applying FFPE samples …

Challenges for pathologists in implementing clinical microbiome diagnostic testing

Y Gerasimova, H Ali, U Nadeem - The Journal of Pathology …, 2024 - Wiley Online Library
Recent research has established that the microbiome plays potential roles in the
pathogenesis of numerous chronic diseases, including carcinomas. This discovery has led …

Biopsy bacterial signature can predict patient tissue malignancy

G Hogan, J Eckenberger, N Narayanen, SP Walker… - Scientific Reports, 2021 - nature.com
Considerable recent research has indicated the presence of bacteria in a variety of human
tumours and matched normal tissue. Rather than focusing on further identification of bacteria …

Characterizing and Exploiting Tumor Microenvironments to Optimize Treatment Outcomes

EH Allott, K Dean, T Robson, C Meaney - 2021 - mdpi.com
Simple Summary The Irish Association for Cancer Research (IACR) held its 57th annual
conference from the 24–26 March 2021 in a virtual format due to the ongoing pandemic …

Sampling and Sample Preparation in Bioanalysis

L Tasic - Tools and Trends in Bioanalytical Chemistry, 2022 - Springer
Many types of samples from the biosphere can be analyzed: a biofluid, an organ, a tissue, a
cell, or even a virus, ie, a viral nanoparticle. There are different types of sampling, for …

Discovering Novel RNA Regions to Develop Biomarkers and Therapeutic Opportunities for Breast Cancer & SARS-CoV-2

B Mistretta - 2020 - uh-ir.tdl.org
Breast cancer accounts for 23% of all cancer deaths and second most related mortality in
women. Recently, advances in the field of immuno-oncology have demonstrated therapeutic …