Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro-Oncology (EANO)
The management of patients with brain metastases has become a major issue due to the
increasing frequency and complexity of the diagnostic and therapeutic approaches. In 2014 …
increasing frequency and complexity of the diagnostic and therapeutic approaches. In 2014 …
Treatment of brain metastases
X Lin, LM DeAngelis - Journal of clinical oncology, 2015 - ascopubs.org
Brain metastases (BMs) occur in 10% to 20% of adult patients with cancer, and with
increased surveillance and improved systemic control, the incidence is likely to grow …
increased surveillance and improved systemic control, the incidence is likely to grow …
Radiation therapy for brain metastases: an ASTRO clinical practice guideline
Purpose This guideline provides updated evidence-based recommendations addressing
recent developments in the management of patients with brain metastases, including …
recent developments in the management of patients with brain metastases, including …
Effect of radiosurgery alone vs radiosurgery with whole brain radiation therapy on cognitive function in patients with 1 to 3 brain metastases: a randomized clinical trial
PD Brown, K Jaeckle, KV Ballman, E Farace… - Jama, 2016 - jamanetwork.com
Importance Whole brain radiotherapy (WBRT) significantly improves tumor control in the
brain after stereotactic radiosurgery (SRS), yet because of its association with cognitive …
brain after stereotactic radiosurgery (SRS), yet because of its association with cognitive …
The evolving landscape of brain metastasis
Metastasis, involving the spread of systemic cancer to the brain, results in neurologic
disability and death. Current treatments are largely palliative in nature; improved therapeutic …
disability and death. Current treatments are largely palliative in nature; improved therapeutic …
Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomised controlled trial
Background It is unclear whether the benefit of adding whole-brain radiation therapy
(WBRT) to stereotactic radiosurgery (SRS) for the control of brain-tumours outweighs the …
(WBRT) to stereotactic radiosurgery (SRS) for the control of brain-tumours outweighs the …
A European Organisation for Research and Treatment of Cancer phase III trial of adjuvant whole-brain radiotherapy versus observation in patients with one to three …
R Soffietti, M Kocher, UM Abacioglu, S Villa… - Journal of clinical …, 2013 - ascopubs.org
Purpose This phase III trial compared adjuvant whole-brain radiotherapy (WBRT) with
observation after either surgery or radiosurgery of a limited number of brain metastases in …
observation after either surgery or radiosurgery of a limited number of brain metastases in …
[HTML][HTML] Radiotherapeutic and surgical management for newly diagnosed brain metastasis (es): An American Society for Radiation Oncology evidence-based …
Purpose To systematically review the evidence for the radiotherapeutic and surgical
management of patients newly diagnosed with intraparenchymal brain metastases. Methods …
management of patients newly diagnosed with intraparenchymal brain metastases. Methods …
Diagnosis-specific prognostic factors, indexes, and treatment outcomes for patients with newly diagnosed brain metastases: a multi-institutional analysis of 4,259 …
PURPOSE: Controversy endures regarding the optimal treatment of patients with brain
metastases (BMs). Debate persists, despite many randomized trials, perhaps because BM …
metastases (BMs). Debate persists, despite many randomized trials, perhaps because BM …
Intracranial Efficacy of Selpercatinib in RET Fusion-Positive Non–Small Cell Lung Cancers on the LIBRETTO-001 Trial
Purpose: We report the intracranial efficacy of selpercatinib, a highly potent and selective
RET inhibitor, approved in the United States for RET fusion-positive non–small cell lung …
RET inhibitor, approved in the United States for RET fusion-positive non–small cell lung …