Objectives Hypericin is a polycyclic aromatic naphthodianthrone that occurs naturally. It is
also an active ingredient in some species of the genus Hypericum. Emerging evidence …

Simple Summary Malignant gliomas are of the deadliest, most hard-to-treat cancers, given
their various characteristics of aggression and infiltration as well as the location of growth …

Hypericin is considered a potent photosensitizer for use in antitumor and antimicrobial
photodynamic therapy (PDT). This review presents the primary biological results obtained …

Hypericin is a naturally occurring compound synthesized by certain species of the genus
Hypericum, with various pharmacological effects. It is used as a natural photosensitizing …

Background Fusarium has been considered an opportunistic pathogen, causing several
infections in humans, including onychomycosis. In addition, a high resistance to …

Cancer is a main cause of death and preferred methods of therapy depend on the type of
tumor and its location. Gliomas are the most common primary intracranial tumor, accounting …

Natural polyphenols, curcumin, rottlerin and EGCG were selected for initial computational
modeling of protein-ligand interaction patterns. The docking calculations demonstrated that …

Photodynamic therapy (PDT) is a relatively novel type of tumor therapy method with low
toxicity and limited side-effects. The aim of the present study was to investigate the …

Cancer as a major public health problem is a big trouble to be cured at present in the world.
Thus, it is essential to discover better anticancer drugs to treat cancer patients. It has been …

Abstract Introduction Protein kinase C (PKC) is a promising drug target for various
therapeutic areas. Natural products derived from plants, animals, microorganisms, and …