Synthetic approaches to monofluoroalkenes

G Landelle, M Bergeron, MO Turcotte-Savard… - Chemical Society …, 2011 - pubs.rsc.org
Monofluoroalkenes are an important fluorinated class of compounds with applications in
medicinal chemistry, material sciences and organic chemistry. An overview of methods …

Palladium-and/or copper-mediated cross-coupling reactions between 1-alkynes and vinyl, aryl, 1-alkynyl, 1, 2-propadienyl, propargyl and allylic halides or related …

R Rossi, A Carpita, F Bellina - Organic preparations and …, 1995 - Taylor & Francis
The reaction between 1-alkynes and aryl or vinyl halides, in the presence of a base and a
palladium (II) or a palladium (0) catalyst as well as of copper (1) iodide as an effective …

Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-β ligands

MS Malamas, ES Manas, RE McDevitt… - Journal of medicinal …, 2004 - ACS Publications
New diphenolic azoles as highly selective estrogen receptor-β agonists are reported. The
more potent and selective analogues of these series have comparable binding affinities for …

Building block approaches to aliphatic organofluorine compounds

JM Percy - Organofluorine Chemistry: Techniques and Synthons, 1997 - Springer
This review deals with general and significant developments in the area of building block
chemistry of lightly-fluorinated aliphatic compounds, that is, those that contain one, two, or …

Fluorinated resveratrol and pterostilbene

S Eddarir, Z Abdelhadi, C Rolando - Tetrahedron Letters, 2001 - Elsevier
A general method for the synthesis of polyhydroxylated stilbene monofluorinated on the
central double bond based on the Suzuki reaction between a bromofluoroolefin and a …

A concise synthesis of enantioenriched fluorinated carbocycles.

Y Lam, C Bobbio, I Cooper… - … Chemie (International ed …, 2007 - ora.ox.ac.uk
(Chemical Equation Presented) A" reverse" cycloaddition-fluorination strategy has been
validated to access enantioenriched fluorinated compounds featuring up to five stereogenic …

Stereoselective synthesis of mono-fluoroalkenes

S Hara - Stereoselective Alkene Synthesis, 2012 - Springer
Abstract Recent developments in the stereoselective synthesis of fluoroalkenes, which
include hydrofluorination of alkyne, fluorination of alkenylmetal, condensation methods …

Selective mono-and dialkynylation of 1-fluoro-2, 2-diiodovinylarenes using Pd-catalyzed decarboxylative coupling reactions

A Jayaraman, S Lee - Organic letters, 2019 - ACS Publications
Palladium-catalyzed decarboxylative coupling reactions using alkynoic acids and 1-fluoro-2,
2-diiodovinylarenes provide mono-and dialkynylfluoroalkenes with high selectivity. When …

An Efficient Stereoselective Synthesis of (E)-β-Fluoroalkenyliodonium Salts

M Yoshida, K Kawakami, S Hara - Synthesis, 2004 - thieme-connect.com
Stereoselective synthesis of (E)-β-fluoroalkenyliodonium salts was performed by the
treatment of alk-1-ynes with p-iodotoluene difluoride in the presence of HBF 4-Et 2 O. The …

Palladium-Catalyzed Stereoconvergent Formylation of (E/Z)-β-Bromo-β-fluorostyrenes: Straightforward Access to (Z)-α-Fluorocinnamic Aldehydes and (Z)-β …

R Zemmouri, M Kajjout, Y Castanet… - The Journal of …, 2011 - ACS Publications
We report here the stereoconvergent formylation of (E/Z)-β-bromo-β-fluorostyrene mixtures
with carbon monoxide and sodium formate catalyzed by palladium. Optimization of reaction …