The origins of our nearly ten‐year research program of chemical and biological
investigations into peptides based on homologated proteinogenic amino acids are …

Abstract α‐Amino acids protected at nitrogen in quite different ways can be transformed
without racemization into the corresponding α‐amino aldehydes. Provided one chooses the …

Fully stereodivergent dual‐catalytic α‐allylation of protected α‐amino‐and α‐
hydroxyacetaldehydes is achieved through iridium‐and amine‐catalyzed substitution of …

The synthesis of optically active organic compounds is one of themost important problems of
contemporary chemistry. Pure enantiomers attain increasing com-mercial interest, especially …

Syntheses of 1, 1-dimethylethyl (S)-4-formyl-2, 2-dimethyl-3-oxazolidinecarboxylate (5) and
1, 1-dimethylethyl (4S-trons)-4-formyl-2, 2, 5-trimethyl-3-oxazolidinecarboxylate (6) from …

For a comparison with the corresponding α‐and β‐hexapeptides H‐(Val‐Ala‐Leu) 2‐OH (A)
and H‐(β‐HVal‐β‐HAla‐β‐HLeu) 2‐OH (B), we have now prepared the corresponding γ …

Anionic substitution of N-(9-(9-phenylfluorenyl))-protected glutamic acidesters proceeds
without loss of optical integrity to give 4-substitutedglutamic acid derivatives. The 4-methyl …

Effective use of the “chiral pool” of natural L‐amino acids is achieved by means of the easily
accessible derivatives 1. Depending on the reagent, 1 reacts stereoselectively under either …

As pharmaceutical companies look to develop single enantiomers as drug candidates,
chemists are increasingly faced with the problems associated with this subclass of organic …

4-Oxoazetidine-2-carbaldehydes or 4-formyl-β-lactams can be considered both as protected
α-amino aldehydes and masked β-amino acids. These bifunctional compounds exhibit a …