The endothelium can evoke relaxations of the underlying vascular smooth muscle, by
releasing vasodilator substances. The best‐characterized endothelium‐derived relaxing …

The endothelium can evoke relaxations (dilatations) of the underlying vascular smooth
muscle, by releasing vasodilator substances. The best characterized endothelium‐derived …

Chronic excessive activation of glucocorticoid receptors induces obesity, insulin resistance,
glucose intolerance, dyslipidaemia and hypertension. Subtle abnormalities of the …

Inappropriate aldosterone and parathyroid hormone (PTH) secretion is strongly linked with
development and progression of cardiovascular (CV) disease. Accumulating evidence …

Obese individuals frequently develop hypertension, which is for an important part
attributable to renin-angiotensin-aldosterone system (RAAS) overactivity. This review …

The mineralocorticoid receptor (MR), a member of the steroid receptor family, regulates
blood pressure by mediating the effects of the hormone aldosterone (Aldo) on renal sodium …

Aims Evidence has accumulated that elevated aldosterone levels are associated with
increased risks of fatal cardiovascular (CV) events. With the present analysis, we aimed at …

Metabolic syndrome is an obesity-associated collection of disorders, each of which
contributes to cardiovascular risk. Metabolic syndrome is also associated with …

In the setting of primary aldosteronism, elevated aldosterone levels are associated with
increased blood pressure. Aldosterone concentrations within the normal range, however …

Cardiovascular (CV) stiffening represents a complex series of events evolving from
pathological changes in individual cells of the vasculature and heart which leads to overt …