Collective cell migration has a key role during morphogenesis and during wound healing
and tissue renewal in the adult, and it is involved in cancer spreading. In addition to …

During embryonic development, tissues undergo major rearrangements that lead to germ
layer positioning, patterning, and organ morphogenesis. Often these morphogenetic …

Membrane protrusions at the leading edge of cells, known as lamellipodia, drive cell
migration in many normal and pathological situations. Lamellipodial protrusion is powered …

Cells migrate in multiple different ways depending on their environment, which includes the
extracellular matrix composition, interactions with other cells, and chemical stimuli. For all …

Connexins are the primary components of gap junctions, providing direct links between cells
under many physiological processes. Here, we demonstrate that in addition to this canonical …

Contact inhibition of locomotion (CIL) is the process through which cells move away from
each other after cell-cell contact, and it contributes to malignant invasion and developmental …

Contact inhibition of locomotion (CIL) is a process whereby a cell ceases motility or changes
its trajectory upon collision with another cell. CIL was initially characterized more than half a …

Collective cell chemotaxis, the directed migration of cell groups along gradients of soluble
chemical cues, underlies various developmental and pathological processes. We use neural …

The migratory dynamics of cells in physiological processes, ranging from wound healing to
cancer metastasis, rely on contact-mediated cell–cell interactions. These interactions play a …

Our understanding of the neural crest, a key vertebrate innovation, is built upon studies of
multiple model organisms. Early research on neural crest cells (NCCs) was dominated by …