Scavenger receptor structure and function in health and disease

I Abdul Zani, SL Stephen, NA Mughal, D Russell… - Cells, 2015 - mdpi.com
Scavenger receptors (SRs) are a 'superfamily'of membrane-bound receptors that were
initially thought to bind and internalize modified low-density lipoprotein (LDL), though it is …

Mechanisms of mammalian iron homeostasis

K Pantopoulos, SK Porwal, A Tartakoff… - Biochemistry, 2012 - ACS Publications
Iron is vital for almost all organisms because of its ability to donate and accept electrons with
relative ease. It serves as a cofactor for many proteins and enzymes necessary for oxygen …

A consensus definitive classification of scavenger receptors and their roles in health and disease

MR PrabhuDas, CL Baldwin, PL Bollyky… - The Journal of …, 2017 - journals.aai.org
Scavenger receptors constitute a large family of proteins that are structurally diverse and
participate in a wide range of biological functions. These receptors are expressed …

[PDF][PDF] Long noncoding RNA TSLNC8 is a tumor suppressor that inactivates the interleukin‐6/STAT3 signaling pathway

J Zhang, Z Li, L Liu, Q Wang, S Li, D Chen, Z Hu… - …, 2018 - Wiley Online Library
Long noncoding RNAs can serve as oncogenes or tumor suppressors in human cancer;
however, their biological functions and underlying mechanism in hepatocarcinogenesis are …

Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression

SA Selamat, BS Chung, L Girard, W Zhang… - Genome …, 2012 - genome.cshlp.org
Lung cancer is the leading cause of cancer death worldwide, and adenocarcinoma is its
most common histological subtype. Clinical and molecular evidence indicates that lung …

The significance of ferritin in cancer: anti-oxidation, inflammation and tumorigenesis

AA Alkhateeb, JR Connor - Biochimica et Biophysica Acta (BBA)-Reviews …, 2013 - Elsevier
The iron storage protein ferritin has been continuously studied for over 70 years and its
function as the primary iron storage protein in cells is well established. Although the …

Altered microRNA expression profile with miR-146a upregulation in CD4+T cells from patients with rheumatoid arthritis

J Li, Y Wan, Q Guo, L Zou, J Zhang, Y Fang… - Arthritis research & …, 2010 - Springer
Introduction Increasing evidence indicates that microRNAs (miRNAs) play a critical role in
the pathogenesis of inflammatory diseases. The aim of the study was to investigate the …

The conserved scavenger receptor cysteine-rich superfamily in therapy and diagnosis

VG Martínez, SK Moestrup, U Holmskov… - Pharmacological …, 2011 - ASPET
The scavenger receptor cysteine-rich (SRCR) superfamily of soluble or membrane-bound
protein receptors is characterized by the presence of one or several repeats of an ancient …

[PDF][PDF] αB‐crystallin complexes with 14‐3‐3ζ to induce epithelial‐mesenchymal transition and resistance to sorafenib in hepatocellular carcinoma

XY Huang, AW Ke, GM Shi, X Zhang, C Zhang… - …, 2013 - Wiley Online Library
The overall survival of patients with hepatocellular carcinoma (HCC) remains poor, and the
molecular pathogenesis remains incompletely defined in HCC. Here we report that …

A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions

W Xue, T Kitzing, S Roessler, J Zuber… - Proceedings of the …, 2012 - National Acad Sciences
The large chromosomal deletions frequently observed in cancer genomes are often thought
to arise as a “two-hit” mechanism in the process of tumor-suppressor gene (TSG) …