Salivary proteins and microbiota as biomarkers for early childhood caries risk assessment

AS Hemadi, R Huang, Y Zhou, J Zou - International journal of oral …, 2017 - nature.com
Early childhood caries (ECC) is a term used to describe dental caries in children aged 6
years or younger. Oral streptococci, such as Streptococcus mutans and Streptococcus …

Saliva as a diagnostic tool for dental caries, periodontal disease and cancer: is there a need for more biomarkers?

MAR Buzalaf, AC Ortiz, TS Carvalho… - Expert review of …, 2020 - Taylor & Francis
Introduction: A biomarker is a biological indicator of normal or pathogenic processes.
Identification of biomarkers is useful for the prevention, diagnosis and prognosis of diseases …

Mother-to-child transmission of Streptococcus mutans: a systematic review and meta-analysis

VA da Silva Bastos, LB Freitas-Fernandes… - Journal of dentistry, 2015 - Elsevier
Objectives A systematic review was performed with the aim of determining whether there is
scientific evidence of the transmission of Streptococcus mutans from mother to child. Data …

Protein‐based salivary profiles as novel biomarkers for oral diseases

AI Lorenzo-Pouso, M Pérez-Sayáns, SB Bravo… - Disease …, 2018 - Wiley Online Library
The Global Burden of Oral Diseases affects 3.5 billion people worldwide, representing the
number of people affected by the burden of untreated dental caries, severe periodontal …

Salivary protein roles in oral health and as predictors of caries risk

G Laputková, V Schwartzová, J Bánovčin… - Open life …, 2018 - degruyter.com
This work describes the current state of research on the potential relationship between
protein content in human saliva and dental caries, which remains among the most common …

The human oral metaproteome reveals potential biomarkers for caries disease

P Belda‐Ferre, J Williamson, Á Simón‐Soro… - …, 2015 - Wiley Online Library
Tooth decay is considered the most prevalent human disease worldwide. We present the
first metaproteomic study of the oral biofilm, using different mass spectrometry approaches …

Social-biological interactions in oral disease: A 'cells to society'view

N Gomaa, M Glogauer, H Tenenbaum, A Siddiqi… - Plos one, 2016 - journals.plos.org
Oral diseases constitute a major worldwide public health problem, with their burden
concentrating in socially disadvantaged and less affluent groups of the population, resulting …

Mass spectrometry‐based proteomic approaches for salivary protein biomarkers discovery and dental caries diagnosis: A critical review

P Ahmad, A Hussain… - Mass Spectrometry …, 2024 - Wiley Online Library
Dental caries is a multifactorial chronic disease resulting from the intricate interplay among
acid‐generating bacteria, fermentable carbohydrates, and several host factors such as …

Differentially expressed salivary proteins in dental caries patients

ZM Khan, H Waheed, Z Khurshid… - BioMed research …, 2021 - Wiley Online Library
Dental caries is a multifactorial disease mainly caused by cariogenic bacteria commonly
found in the oral cavity. Dental caries may cause demineralization of the tooth, cavitation …

Human salivary proteins and their peptidomimetics: Values of function, early diagnosis, and therapeutic potential in combating dental caries

K Wang, X Zhou, W Li, L Zhang - Archives of Oral Biology, 2019 - Elsevier
Saliva contains a large number of proteins that play various crucial roles to maintain the oral
health and tooth integrity. This oral fluid is proposed to be one of the most important host …