Oxidative stress defines a condition in which the prooxidant–antioxidant balance in the cell
is disturbed, resulting in DNA hydroxylation, protein denaturation, lipid peroxidation, and …

Reactive oxygen species (ROS), a redox signal, are produced by various enzymatic
reactions and chemical processes, which are essential for many physiological functions and …

Background Brain injury results in an increase in the activity of the reactive oxygen species
generating NADPH oxidase (NOX) enzymes. Preliminary studies have shown that NOX2 …

This paper reviews the potential role of glutathione (GSH) in autism spectrum disorder
(ASD). GSH plays a key role in the detoxification of xenobiotics and maintenance of balance …

Significance: The oxidative stress, resulting from an imbalance in the production and
scavenging of reactive oxygen species (ROS), is known to be involved in the development …

Kinins are generated within inflammatory tissue microenvironments, where they exert
diverse functions, including cell proliferation, leukocyte activation, cell migration, endothelial …

Bradykinin (BK) induces inflammation in rheumatoid arthritis (RA). Resveratrol is a potent
activator of Sirt1 which could modulate inflammation through deacetylating histones of …

Neurological disorders represent major health concerns in terms of comorbidity and
mortality worldwide. Despite a tremendous increase in our understanding of the …

Ischemic stroke and Alzheimer's disease (AD), despite being distinct disease entities, share
numerous pathophysiological mechanisms such as those mediated by inflammation …

Organophosphates (OPs) are toxic chemicals produced by an esterification process and
some other routes. They are the main components of herbicides, pesticides, and insecticides …