Potential and therapeutic roles of diosmin in human diseases

E Huwait, M Mobashir - Biomedicines, 2022 - mdpi.com
Because of their medicinal characteristics, effectiveness, and importance, plant-derived
flavonoids have been a possible subject of research for many years, particularly in the last …

The effectiveness of patient-centered care vs. usual care in type 2 diabetes self-management: a systematic review and meta-analysis

K Asmat, K Dhamani, R Gul, ES Froelicher - Frontiers in public health, 2022 - frontiersin.org
Background Patient-centered care in diabetes self-management might be a significant factor
in improving health outcomes of adults with type 2 diabetes, yet the supporting evidence is …

Molecular genetics of abnormal redox homeostasis in type 2 diabetes mellitus

I Azarova, A Polonikov, E Klyosova - International Journal of Molecular …, 2023 - mdpi.com
Numerous studies have shown that oxidative stress resulting from an imbalance between
the production of free radicals and their neutralization by antioxidant enzymes is one of the …

Integrative multi-omics approaches to explore immune cell functions: Challenges and opportunities

X Wang, D Fan, Y Yang, RC Gimple, S Zhou - IScience, 2023 - cell.com
As modern biological sciences evolve from investigation of individual molecules and
pathways to growing emphasis on global and systems-based processes, increasing efforts …

Synthesis of silver nano particles using myricetin and the in-vitro assessment of anti-colorectal cancer activity: In-silico integration

ST Anwer, M Mobashir, OI Fantoukh, B Khan… - International Journal of …, 2022 - mdpi.com
The creation of novel anticancer treatments for a variety of human illnesses, including
different malignancies and dangerous microbes, also potentially depends on nanoparticles …

Multi-staged gene expression profiling reveals potential genes and the critical pathways in kidney cancer

HI Khouja, IM Ashankyty, LH Bajrai, PKP Kumar… - Scientific Reports, 2022 - nature.com
Cancer is among the highly complex disease and renal cell carcinoma is the sixth-leading
cause of cancer death. In order to understand complex diseases such as cancer, diabetes …

An approach for systems-level understanding of prostate cancer from high-throughput data integration to pathway modeling and simulation

M Mobashir, SP Turunen, MA Izhari, IM Ashankyty… - Cells, 2022 - mdpi.com
To understand complex diseases, high-throughput data are generated at large and multiple
levels. However, extracting meaningful information from large datasets for comprehensive …

A network-guided approach to discover phytochemical-based anticancer therapy: Targeting MARK4 for hepatocellular carcinoma

S Ahmed, M Mobashir, LA Al-Keridis… - Frontiers in …, 2022 - frontiersin.org
MAP/microtubule affinity-regulating kinase 4 (MARK4) is associated with various biological
functions, including neuronal migration, cell polarity, microtubule dynamics, apoptosis, and …

Genomic profiling and network-level understanding uncover the potential genes and the pathways in hepatocellular carcinoma

SA El-Kafrawy, MM El-Daly, LH Bajrai… - Frontiers in …, 2022 - frontiersin.org
Data integration with phenotypes such as gene expression, pathways or function, and
protein-protein interactions data has proven to be a highly promising technique for …

Gene Expression Profiling of Early Acute Febrile Stage of Dengue Infection and Its Comparative Analysis With Streptococcus pneumoniae Infection

LH Bajrai, SS Sohrab, TA Alandijany… - Frontiers in Cellular …, 2021 - frontiersin.org
Infectious diseases are the disorders caused by organisms such as bacteria, viruses, fungi,
or parasites. Although many of them are permentantly hazardous, a number of them live in …