Inflammatory immune response plays a key role in reproductive failures such as multiple
implantation failures (MIF), early pregnancy loss, and recurrent pregnancy losses (RPL) …

Extensive evidence suggests that soluble ligands and their receptors mediate human
preimplantation embryo development and implantation. Progress in this complex area has …

Although IVF has been performed routinely for many years to help couples with fertility
problems and in relation to modern breeding of farm animals, pregnancy rates after transfer …

There have been over 8 million babies born through in vitro fertilization (IVF) and this
number continues to grow. There is a global trend to perform elective single embryo …

The nonclassical HLA-G molecule is a trophoblast-specific molecule present in almost every
pregnancy. It differs from classical HLA class I molecules by the low degree of allelic variants …

OBJECTIVE: To compare embryologic and clinical outcomes in terms of preimplantation
development, implantation, pregnancy rates, and secretome profile of implanted blastocysts …

BACKGROUND The human leucocyte antigen (HLA) class Ib molecules, HLA-E,-F and-G,
are expressed at the materno-fetal interface. Because of the apparent immunoregulatory …

Definite causes for several pathologies of pregnancy remain unknown. In light of several
recent studies, however, diminished or aberrant HLA-G expression may be associated with …

The HLA-G molecule is widely accepted as an important factor for pregnancy success. Its
expression has been detected in the extravillous trophoblasts. Soluble HLA-G (sHLA-G) was …

OBJECTIVE: To identify factors secreted by the human embryo and correlate levels with
embryo morphology and pregnancy outcome. DESIGN: A laboratory-based study of human …